The Baboon Model for Dental Development

  • Leslea J. Hlusko
  • Michael C. Mahaney
Part of the Developments in Primatology: Progress and Prospects book series (DIPR)

The dental research implications of the physiological, immunological, and morphological similarities between baboons and humans have long been recognized (Virgadamo et al., 1972; Aufdemorte et al., 1993). Applied dentistry has widely employed the baboon as a model upon which to develop procedures and techniques and to test the material biocompatibility prior to introduction into general practice on humans. For example, baboons have been used for the tests of procedures to mechanically modify jaw bone growth (Bell et al., 1999), tests of responses to allograft mixtures for bony reconstructions (Kohles et al., 2000), development for therapeutic osteogenesis and functional and morphological bone repair techniques (Ripamonti, 1992), tests of gene products (such as BMP proteins) to induce periodontal regeneration (Ripamonti et al., 2001), protocols for stabilizing jaws for treating fractures (Fisher et al., 1990), assessments of bone response to prosthetic fit (Carr et al., 1996), and tests of responses to orthodontic apparatus (Woods and Nanda, 1991).


Quantitative Trait Locus Dental Development Supernumerary Tooth Enamel Defect Amelogenesis Imperfecta 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Leslea J. Hlusko
    • 1
  • Michael C. Mahaney
    • 2
    • 3
  1. 1.Department of Integrative BiologyUniversity of CaliforniaBerkeley
  2. 2.Department of GeneticsSouthwest Foundation for Biomedical ResearchSan Antonio
  3. 3.Southwest National Primate Research Center, Southwest Foundation for Biomedical ResearchSan Antonio

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