Psychiatric Genetics-An Update

  • Prashant Gajwani


Over the last decade, there has been an exponential growth in understanding psychiatric illnesses with an expanded array of available treatments. The physical expression of characteristics coded by genes is known as a phenotype. The phenotype of psychiatric disorders is based on an intricate system of symptom classification which has evolved over the last several decades (American Psychiatric Association, 1994). With a better understanding of illness phenotype and comorbidities, researchers and clinicians have been able to refine treatment options.

Genetic factors play a fundamental role in the genesis of psychiatric disorders. In addition, genetic factors may also play a very important role in metabolism, distribution, and eventual response to psychotropic medications. The identification of underlying genetic variations associated with psychiatric illnesses could help us evaluate risk factors for developing phenotype targeted pharmacotherapy agents and medication doses on...


Psychiatric Disorder Bipolar Disorder Major Depressive Disorder Stevens Johnson Syndrome Psychiatric Medication 
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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.University Hospitals Case Medical Center, School of Medicine, Case Western Reserve UniversityCleveland

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