Imaging Cardiac Tumors

  • Mannudeep K. Kalra
  • Suhny Abbara
Part of the Cancer Treatment and Research book series (CTAR, volume 143)

Imaging of the heart has evolved rapidly in the last decade. With rapid advances in computed tomography (CT) and the introduction of multislice CT, it is possible to image the heart in less than a 10 seconds breath-hold [1]. Magnetic resonance imaging (MRI) of the heart has evolved to become the imaging modality of choice for evaluation of pericardial and cardiac tumors [2]. This chapter addresses the role of cross-sectional imaging, particularly CT and MRI, for evaluation of cardiac tumors.


Compute Tomography Coronary Angiography Cardiac Tumor Constrictive Pericarditis Cardiac Myxoma Cardiac Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Kalra MK, Maher MM, D’Souza R, Saini S. Multidetector computed tomography technology: current status and emerging developments. J Comput Assist Tomogr. 2004;28 Suppl 1:S2-6.CrossRefGoogle Scholar
  2. 2.
    Schvartzman PR, White RD. Imaging of cardiac and paracardiac masses. J thorac Imaging. 2000;15:265–73.PubMedCrossRefGoogle Scholar
  3. 3.
    Basso C, Valente M, Poletti A, Casarotto D, Thiene G. Surgical pathology of primary cardiac and pericardial tumors. Eur J Cardiothorac Surg. 1997;12:730–7.PubMedCrossRefGoogle Scholar
  4. 4.
    Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR. Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation.Radiographics. 2000;20:1073–103.PubMedGoogle Scholar
  5. 5.
    Majano-Lainez RA. Cardiac tumors: a current clinical and pathological perspective. Crit Rev Oncog. 1997;8:293–303.PubMedGoogle Scholar
  6. 6.
    Hoffmeier A, Schmid C, Deiters S, Drees G, Rothenburger M, Tjan TD, Schmidt C, Loher A, Maintz D, Spieker T, Mesters RM, Scheld HH. Neoplastic heart disease–the Muenster experience with 108 patients. Thorac Cardiovasc Surg. 2005;53:1–8.PubMedCrossRefGoogle Scholar
  7. 7.
    Endo A, Ohtahara A, Kinugawa T, Nawada T, Fujimoto Y, Mashiba H, Shigemasa C. Clinical incidence of primary cardiac tumors. J Cardiol. 1996;28:227–34.PubMedGoogle Scholar
  8. 8.
    Odim J, Reehal V, Laks H, Mehta U, Fishbein MC. Surgical pathology of cardiac tumors. Two decades at an urban institution. Cardiovasc Pathol. 2003 Sep;12:267–70.PubMedCrossRefGoogle Scholar
  9. 9.
    Piazza N, Chughtai T, Toledano K, Sampalis J, Liao C, Morin JF. Primary cardiac tumours: eighteen years of surgical experience on 21 patients. Can J Cardiol. 2004;20:1443–8.PubMedGoogle Scholar
  10. 10.
    Thomas-de-Montpreville V, Nottin R, Dulmet E, Serraf A. Heart tumors in children and adults: clinicopathological study of 59 patients from a surgical center. Cardiovasc Pathol. 2007;16:22–8.PubMedCrossRefGoogle Scholar
  11. 11.
    Butany J, Nair V, Naseemuddin A, Nair GM, Catton C, Yau T. Cardiac tumors: diagnosis and management. Lancet Oncol. 2005;6:219–28.PubMedCrossRefGoogle Scholar
  12. 12.
    Limet R. The beginnings of cardiac surgery. Rev Med Liege. 2006;61:812–9.PubMedGoogle Scholar
  13. 13.
    Broderick LS, Brooks GN, Kuhlman JE. Anatomic pitfalls of the heart and pericardium. Radiographics. 2005;25:441–53.PubMedCrossRefGoogle Scholar
  14. 14.
    Kaminaga T, Takeshita T, Kimura I. Role of magnetic resonance imaging for evaluation of tumors in the cardiac region. Eur Radiol. 2003;13 Suppl 4:L1–10Google Scholar
  15. 15.
    Gulati G, Sharma S, Kothari SS, Juneja R, Saxena A, Talwar KK. Comparison of echo and MRI in the imaging evaluation of intracardiac masses. Cardiovasc Intervent Radiol. 2004;27(5):459–69.PubMedCrossRefGoogle Scholar
  16. 16.
    Araoz PA, Mulvagh SL, Tazelaar HD, Julsrud PR, Breen JF. CT and MRI of benign primary cardiac neoplasms with echocardiographic correlation. Radiographics. 2000;20:1303–19.PubMedGoogle Scholar
  17. 17.
    Krombach GA, Spuentrup E, Buecker A, Mahnken AH, Katoh M, Temur Y, Higgins CB, Gunther RW. Heart tumors: magnetic resonance imaging and multislice spiral CT. Rofo. 2005;177:1205–18.PubMedGoogle Scholar
  18. 18.
    Chiles C, Woodard PK, Gutierrez FR, Link KM. Metastatic involvement of the heart and pericardium: CT and MRI. Radiographics. 2001;21:439–49.PubMedGoogle Scholar
  19. 19.
    Restrepo CS, Largoza A, Lemos DF, Diethelm L, Koshy P, Castillo P, Gomez R, Moncada R, Pandit M.CT and MRI findings of malignant cardiac tumors. Curr Probl Diagn Radiol. 2005;34:1–11.PubMedCrossRefGoogle Scholar
  20. 20.
    Restrepo CS, Largoza A, Lemos DF, Diethelm L, Koshy P, Castillo P, Gomez R, Moncada R, Pandit M.CT and MRI findings of benign cardiac tumors. Curr Probl Diagn Radiol. 2005;34:12–21.PubMedCrossRefGoogle Scholar
  21. 21.
    Ragland MM, Tak T.The role of echocardiography in diagnosing space-occupying lesions of the heart. Clin Med Res. 2006;4:22–32PubMedCrossRefGoogle Scholar
  22. 22.
    Sparrow PJ, Kurian JB, Jones TR, Sivananthan MU. MRI of cardiac tumors. Radiographics. 2005;25:1255–76.PubMedCrossRefGoogle Scholar
  23. 23.
    Baldassarre S, Cappeliez O, Leone A, Divano L.Cardiac magnetic resonance. Myth and reality. Rev Med Brux. 2004;25:80–6.PubMedGoogle Scholar
  24. 24.
    Luna A, Ribes R, Caro P, Vida J, Erasmus JJ. Evaluation of cardiac tumors with magnetic resonance imaging. Eur Radiol. 2005;15:1446–55.PubMedCrossRefGoogle Scholar
  25. 25.
    Nazarian S, Roguin A, Zviman MM, Lardo AC, Dickfeld TL, Calkins H, Weiss RG, Berger RD, Bluemke DA, Halperin HR. Clinical utility and safety of a protocol for noncardiac and cardiac magnetic resonance imaging of patients with permanent pacemakers and implantable-cardioverter defibrillators at 1.5 tesla. Circulation. 2006;114:1277–84PubMedCrossRefGoogle Scholar
  26. 26.
    Mollet NR, Cademartiri F, Van Mieghem C, Meijboom B, Pugliese F, Runza G, Baks T, Dikkeboer J, McFadden EP, Freericks MP, Kerker JP, Zoet SK, Boersma E, Krestin GP, de Feyter PJ. Adjunctive value of CT coronary angiography in the diagnostic work-up of patients with typical angina pectoris. Eur Heart J. 2007 Mar 9; [Epub ahead of print].Google Scholar
  27. 27.
    Schussler JM, Smith ER. Sixty-four-slice computed tomographic coronary angiography: will the “triple rule out” change chest pain evaluation in the ED? Am J Emerg Med. 2007;25:367–75.PubMedCrossRefGoogle Scholar
  28. 28.
    Rispler S, Keidar Z, Ghersin E, Roguin A, Soil A, Dragu R, Litmanovich D, Frenkel A, Aronson D, Engel A, Beyar R, Israel O. Integrated single-photon emission computed tomography and computed tomography coronary angiography for the assessment of hemodynamically significant coronary artery lesions. J Am Coll Cardiol. 2007;49:1059–67.PubMedCrossRefGoogle Scholar
  29. 29.
    Meijboom WB, Mollet NR, van Mieghem CA, Weustink AC, Pugliese F, van Pelt N, Cademartiri F, Vourvouri E, de Jaegere P, Krestin GP, de Feyter PJ. 64-slice Computed Tomography Coronary Angiography in Patients with Non-ST Elevation Acute Coronary Syndrome. Heart. 2007 Mar 7; [Epub ahead of print].Google Scholar
  30. 30.
    Dewey M, Hamm B. CT Coronary Angiography: Examination Technique, Clinical Results, and Outlook on Future Developments. Rofo. 2007;179:246–260.PubMedGoogle Scholar
  31. 31.
    Kar AK, Roy S, Chatterjee A, Banerjee A, Panja M, Mitra S. Cardiac tumors: an observational study. Indian Heart J. 1996;48:257–60.PubMedGoogle Scholar
  32. 32.
    Tatli S, Lipton MJ.CT for intracardiac thrombi and tumors. Int J Cardiovasc Imaging. 2005;21:115–31.PubMedCrossRefGoogle Scholar
  33. 33.
    Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastases. J Clin Pathol. 2007;60:27–34.PubMedCrossRefGoogle Scholar
  34. 34.
    Sarjeant JM, Butany J, Cusimano RJ. Cancer of the heart: epidemiology and management of primary tumors and metastases. Am J Cardiovasc Drugs. 2003;3:407–21.PubMedCrossRefGoogle Scholar
  35. 35.
    Butany J, Leong SW, Carmichael K, Komeda M. A 30-year analysis of cardiac neoplasms at autopsy. Can J Cardiol. 2005;21:675–80.PubMedGoogle Scholar
  36. 36.
    Forman MB, Byrd BF 3rd, Oates JA, Robertson RM. Two-dimensional echocardiography in the diagnosis of carcinoid heart disease. Am Heart J. 1984;107:492–6.PubMedCrossRefGoogle Scholar
  37. 37.
    Mollet NR, Dymarkowski S, Bogaert J. MRI and CT revealing carcinoid heart disease. Eur Radiol. 2003;13 Suppl 6:L14–8.CrossRefGoogle Scholar
  38. 38.
    Boxt LM. CT of valvular heart disease. Int J Cardiovasc Imaging. 2005;21:105–13.PubMedCrossRefGoogle Scholar
  39. 39.
    Vogel-Claussen J, Pannu H, Spevak PJ, Fishman EK, Bluemke DA. Cardiac valve assessment with MRI and 64-section multi-detector row CT. Radiographics. 2006 Nov-Dec;26(6): 1769–84.PubMedCrossRefGoogle Scholar
  40. 40.
    Freudenberg LS, Rosenbaum SJ, Schulte-Herbruggen J, Eising EG, Lauenstein T, Wolff A, Bockisch A. Diagnosis of a cardiac angiosarcoma by fluorine-18 fluordeoxyglucose positron emission tomography. Eur Radiol. 2002;12 Suppl 3:S158–61.PubMedGoogle Scholar
  41. 41.
    Juergens KU, Hoffmeier A, Riemann B, Maintz D. Early detection of local tumour recurrence and pulmonary metastasis in cardiac angiosarcoma with PET-CT and MRI. Eur Heart J. 2007;28:663.PubMedCrossRefGoogle Scholar
  42. 42.
    Ryu SJ, Choi BW, Choe KO. CT and MR findings of primary cardiac lymphoma: report upon 2 cases and review. Yonsei Med J. 2001;42:451–6.PubMedGoogle Scholar
  43. 43.
    Ikeda H, Nakamura S, Nishimaki H, Masuda K, Takeo T, Kasai K, Ohashi T, Sakamoto N, Wakida Y, Itoh G. Primary lymphoma of the heart: case report and literature review. Pathol Int. 2004;54:187–95.PubMedCrossRefGoogle Scholar
  44. 44.
    Eren NT, Akar AR. Primary pericardial mesothelioma. Curr Treat Options Oncol. 2002;3:369–73.PubMedCrossRefGoogle Scholar
  45. 45.
    Oreopoulos G, Mickleborough L, Daniel L, De Sa M, Merchant N, Butany J. Primary pericardial mesothelioma presenting as constrictive pericarditis. Can J Cardiol. 1999;15:1367–72.PubMedGoogle Scholar
  46. 46.
    Wintersperger BJ, Becker CR, Gulbins H, Knez A, Bruening R, Heuck A, Reiser MF. Tumors of the cardiac valves: imaging findings in magnetic resonance imaging, electron beam computed tomography, and echocardiography. Eur Radiol. 2000;10:443–9.PubMedCrossRefGoogle Scholar
  47. 47.
    Grebenc ML, Rosado-de-Christenson ML, Green CE, Burke AP, Galvin JR. Cardiac myxoma: imaging features in 83 patients. Radiographics. 2002;22:673–89.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Mannudeep K. Kalra
    • 1
  • Suhny Abbara
    • 1
  1. 1.Department of RadiologyMassachusetts General HospitalBostonUSA

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