Acute Respiratory Distress Syndrome

  • Edie Y. Chan

Acute respiratory distress syndrome (ARDS) was first described in 1967 by Ashbaugh and colleagues and was initially associated with trauma, sepsis, or aspirations. In 1994, the American-European Consensus Conference on ARDS created the widely used definition of ARDS as follows: (1) acute onset of severe hypoxemia with a Pao2 to Fio2 ratio of 200mmHg or less, (2) bilateral infiltrates on chest x-ray, and (3) no evidence of left atrial hypertension or a pulmonary wedge pressure less than 18 mmHg. A lesssevere form of ARDS known as ALI (acute lung injury) was also defined at this conference and was distinguished from ARDS by a Pao2 to Fio2 ratio of less than 300mmHg.


Nitric Oxide Acute Lung Injury Acute Respiratory Distress Syndrome Severe Hypoxemia Lung Protective Ventilation 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Edie Y. Chan
    • 1
  1. 1.Department of General Surgery, Division of TransplantRush Medical College of Rush University, Rush University Medical CenterChicagoUSA

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