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Hypercalcemia

  • Michael D. Addis
  • William B. Inabnet

Calcium (Ca) homeostasis is maintained by the action of two hormones on three organ systems. The majority of Ca is stored in bone as hydroxyapatite, a compound that helps maintain structural integrity. Although the intravascular concentration of Ca is small, an imbalance can produce life-threatening symptoms. In plasma, 50% of Ca is unbound or ionized, whereas the remainder is bound to albumin. A change of 1 gm/ dl in serum albumin is associated with a 0.8mg/dl change in total serum calcium. Serum phosphate levels vary inversely with calcium, maintaining a normal concentration product between 30 and 40.

Keywords

Parathyroid Adenoma Parathyroid Carcinoma Neck Exploration Serum Phosphate Level Bilateral Neck Exploration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Michael D. Addis
    • 1
  • William B. Inabnet
    • 2
  1. 1.Department of Vascular SurgerySaint Barnabas Medical CenterSpringfieldUSA
  2. 2.Department of Gastrointestinal and Endocrine SurgeryColumbia UniversityNew YorkUSA

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