Hyperthyroidism is a state of health caused by increased levels of serum thyroxine (T4), or triiodothyronine (T3) or both. Clinical symptoms and signs include weight loss, intolerance to heat, insomnia, loss of hair, flushing, anxiety, tremors, chest pain, palpitation, increased appetite and gastrointestinal motility, amenorrhea, and gynecomastia in males. Metabolic abnormalities include an increase in basal metabolic rate (50%–100%), glycogenolysis, gluconeogenesis, protein catabolism, lipolysis, and free fatty acids. A thyroid storm is a severe state of hyperthyroidism characterized by a rapid increase in temperature, cardiac arrhythmias, circulatory shock, multiorgan failure, and it carries a mortality rate of 10%. It is usually precipitated by stressful conditions such as surgery, infection, and child birth.
KeywordsThyroid Hormone Thyroid Cancer Multinodular Goiter Antithyroid Drug Nodular Goiter
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