Retinoblastoma with Fine Calcification
TC is a 4-year-old girl who was noted by her parents to “not focus on things” with her right eye. She was examined by her pediatrician, who could not see a red reflex in that eye and referred her to a pediatric ophthalmologist, who noted a paramacular mass. B-scan demonstrated a subretinal mass with an irregular surface. A-scan revealed medium and regular internal reflectivity (Fig. 305). Calcium was not detected by either modality. The lesion was assumed to be a noncalcified retinoblastoma and treatment with chemotherapy was begun. She was followed with monthly examination under anesthesia and a small calcified lesion was noted in the left eye 6 months later. This was highly consistent with retinoblastoma. Another course of chemotherapy was instituted and the lesion was noted to regress.