• Edith A. Perez
  • Frances M. Palmieri
  • Shelly M. Brock
Part of the Cancer Treatment and Research book series (CTAR, volume 151)

Systemic adjuvant therapy is regularly recommended for patients diagnosed with invasive breast cancer based on risk of recurrence and likelihood of benefit from therapy. Progress in molecular biology has resulted in the identification and improved understanding of molecular markers that may have prognostic and predictive value for patients with breast cancer. HER2 (human epidermal growth factor receptor 2) is one of the best characterized of these markers and now plays a critical role in patient management.


Overall Survival Left Ventricular Ejection Fraction Human Epidermal Growth Factor Receptor National Comprehensive Cancer Network National Comprehensive Cancer Network 



Funding partially provided by the Breast Cancer Research Foundation.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Edith A. Perez
    • 1
  • Frances M. Palmieri
    • 2
  • Shelly M. Brock
    • 2
  1. 1.Division of Hematology/OncologyInternal Medicine, Mayo ClinicJacksonvilleUSA
  2. 2.Division of Hematology/Oncology and Breast ClinicMayo ClinicJacksonvilleUSA

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