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Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems pp 341–376Cite as

Impedance-Based Biosensors for Pathogen Detection

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Abstract

Electrochemical impedance spectroscopy (EIS) is an important detection technique for biosensors. In the field of immunosensors, and particularly pathogen detection, it is one of the preferred electrochemical techniques because it does away with the use of enzyme labels or redox mediators. This chapter provides an introduction to the fundamentals of EIS and basic data analysis, with an emphasis on the most common features found in immunosensors and possible experimental limitations.

This chapter then discusses a series of functionalisation approaches that can be used in the development of an immunosensor for the detection of bacteria. This is followed by a selection of impedance-based immunosensor examples from the literature.

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Authors and Affiliations

  1. Centro Nacional de Microelectronica IMB-CNM-CSIC; Esfera UAB; Campus Universidad Autónoma de Barcelona, 08193–Bellaterra, Barcelona, Spain

    Xavier Muñoz-Berbel, Neus Godino, Olivier Laczka, Eva Baldrich & Francesc Xavier Muñoz

  2. Instituto de Biotecnología y Biomedicina Departamento de Microbiología y Genética, Universidad Autónoma de Barcelona, 08193–Bellaterra, Barcelona, Spain

    Fco Javier del Campo

Authors
  1. Xavier Muñoz-Berbel
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  2. Neus Godino
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  3. Olivier Laczka
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  4. Eva Baldrich
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  5. Francesc Xavier Muñoz
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  6. Fco Javier del Campo
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Editor information

Editors and Affiliations

  1. Biophage Pharma Inc, Montreal, Canada

    Mohammed Zourob

  2. Consultant to Biophage Pharma Inc, Montreal, Canada

    Souna Elwary

  3. Cranfield University, Bedfordshire, UK

    Anthony Turner

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Muñoz-Berbel, X., Godino, N., Laczka, O., Baldrich, E., Muñoz, F.X., del Campo, F.J. (2008). Impedance-Based Biosensors for Pathogen Detection. In: Zourob, M., Elwary, S., Turner, A. (eds) Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems. Springer, New York, NY. https://doi.org/10.1007/978-0-387-75113-9_15

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  • DOI: https://doi.org/10.1007/978-0-387-75113-9_15

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