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Porous and Planar Silicon Sensors

  • Charles R. Mace
  • Benjamin L. Miller

Abstract

The development of novel sensors able to produce a response directly upon binding of a target biomolecular analyte remains a major area of research in materials science and analytical chemistry. As the primary “raw material” for the microelectronics industry, and because of its biocompatibility and optical properties, silicon has drawn considerable attention in this field. This chapter discusses the current state of efforts in our group and others to develop porous and planar sensors based on silicon. Porous silicon, so-called because of its complex three-dimensional network structure, provides a high internal binding surface and allows for observation of binding by changes in the reflectivity or luminescence spectra of single- or multi-layer devices. Planar silicon sensors, exemplified here by Arrayed Imaging Reflectometry (AIR), do not have the high surface area of porous silicon yet still respond with a high degree of sensitivity to the binding of analytes to the sensing surface. Examples are presented for the use of both types of sensors for the detection of DNA, proteins, and pathogenic bacteria.

Keywords

Surface Plasmon Resonance Porous Silicon Surface Plasmon Resonance Imaging Mesoporous Silicon Macroporous Silicon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Charles R. Mace
    • 1
  • Benjamin L. Miller
    • 1
  1. 1.University of RochesterRochesterUSA

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