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Neurobiological Correlates of Dyslexia

A Review

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Brain Research in Language

Part of the book series: Literacy Studies ((LITS,volume 1))

The selective impairment of reading skills that characterizes dyslexia is a source of difficulty for children and adults in literate societies worldwide. As part of the increasing effort to reveal the underlying causes of this disorder, post-mortem and imaging methodologies are being used to study the neural structures and mechanisms of dyslexics. The following review presents postmortem, structural and functional imaging studies comparing the brains of dyslexic individuals to those of normal readers, focusing particularly on the nature of neural activity at the levels of phonological processing (awareness) and reading, on underlying deficits in the sensory-linguistic transfer of information at the phonological level, and on representational (processing) deficits in the visual pathways of dyslexics. Findings from the post-mortem and structural imaging studies presented attest to various configurational changes associated with dyslexia, particularly in terms of altered hemispheric asymmetry. Research employing functional imaging methods has added to these findings, revealing characteristic changes in neural activation patterns during performance of various sensory and phonological tasks related to reading processes. While a number of brain systems, incorporating frontal, temporal and posterior areas, are shown to be associated with dyslexia, no single mechanism is consistently implicated, such that agreement has yet to be reached regarding the neural basis of the disorder.

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Breznitz, Z., Lebovitz, L. (2008). Neurobiological Correlates of Dyslexia. In: Breznitz, Z. (eds) Brain Research in Language. Literacy Studies, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-74980-8_1

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