Electronic Detection of DNA Adsorption and Hybridization

  • Ulrich Bockelmann
Part of the IFIP International Federation for Information Processing book series (IFIPAICT, volume 249)

We consider a transistor based approach for DNA detection. Immobilization of DNA at different positions of poly(l-lysine) coated field effect transistor arrays is achieved by deposition with a microspotting device or specific hybridization between complementary oligonucleotide sequences. The current voltage characteristics of the transistors are measured with the sample surface immersed in aqueous solution. The chapter provides a brief overview of our experimental technique and of its applications to the detection of DNA adsorption and hybridization.


Research Trend Electronic Detection Reference Spot Nonsyndromic Deafness Salt Dependence 
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Copyright information

© International Federation for Information Processin 2008

Authors and Affiliations

  • Ulrich Bockelmann
    • 1
  1. 1.Laboratoire de Nanobiophysique UMR Gulliver CNRS-ESPCIFrance

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