Signaling Pathways

Part of the CRM Series in Mathematical Physics book series (CRM)

Signaling pathways can be defined by an initiation stage and an effector stage. The initiation phase is triggered by ligand binding to its receptor. This biochemical event generates the effector stage with more or less numerous chemical reactions leading to specific cell responses. Signal propagation can be achieved by proteic complex assemblings, protein activation cascades, protein turnovers, and post-translational modifications of proteins, such as phosphorylation/dephosphorylation, glycosylation, ubiquitination, acetylation, which reversibly modify the properties of involved proteic effectors.


Focal Adhesion Kinase Adenylyl Cyclase Hippo Pathway Inositol Trisphosphate Myosin Light Chain Phosphatase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2008

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