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Vascularized Knee Transplantation

  • Michael Diefenbeck
  • Gunther O. Hofmann

The allogeneic grafting of total joints has been a matter of discussion for almost a century. In 1908, Erich Lexer reported the first transplantation of a human knee joint. The grafting of human joint and tissue were performed without organ preservation techniques, without vascular pedicles and graft reperfusion. Transplantation immunology and the phenomenon of acute and chronic rejection were unknown, as well as immunosuppressive drugs and antibiotics. Hence, Lexer's attempts were doomed to fail.

Keywords

Total Knee Arthroplasty Knee Joint Acute Rejection Immunosuppressive Regime Bone Stock 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2008

Authors and Affiliations

  • Michael Diefenbeck
    • 1
  • Gunther O. Hofmann
    • 2
  1. 1.University of MunichMunichGermany
  2. 2.Department of Surgery, Klinikum GrosshadernLudwig-Maximilians-University MunichMunichGermany

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