Pancreas Biology, Pathology, and Tissue Engineering

  • Wendy M. MacFarlane
  • Adrian J. Bone
  • Moira Harrison


Diabetes is a chronic condition that is increasing at an alarming rate. In 1985, there were approximately 30 million people with diabetes worldwide. Today the International Diabetes Federation estimates that more than 230 million people around the world have diabetes and this total is expected to rise to 350 million by 2025. Not only is diabetes expensive to treat but also the complications of the condition account for 5–10% of total healthcare spending globally. The complications are numerous and devastating, causing blindness, cardiovascular disease, limb amputations, kidney failure, and many more. Until the discovery of insulin in 1921 by Dr. Frederick Grant Banting, Charles Best, James Bertram Collip, and Dr. James Macleod, diabetes was a death sentence. Although the discovery of insulin lead to people surviving where previously they would have died, it was certainly not a cure. It was only after many years of treatment that it became evident that while people could be...


Embryonic Stem Cell Ductal Cell Bone Marrow Derive Stem Cell Adult Pancreas Edmonton Protocol 
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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Wendy M. MacFarlane
    • 1
  • Adrian J. Bone
  • Moira Harrison
  1. 1.School of Pharmacy & Biomolecular SciencesUniversity of BrightonBrighton BN2 4GJUK

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