Conclusions: Towards High-Performance and Industrially Sustainable Tissue Engineering Products

  • Matteo Santin


Since the early 1990s, the research in biomedical field has been dominated by a paradigm shift whereby the concept of replacing damaged tissues and organs with medical devices has been overcome by the goal of their partial or complete regeneration. Although traditional implants (i.e., orthopedic, dental, cardiovascular, and ocular) are still widely used to ameliorate and save patients’ life, it is now possible to engineer materials, bioactive components, and cells able to stimulate the regeneration of tissues damaged by either disease or trauma (Sipe 2002). It has to be outlined that this paradigm shift neither emerged independently nor aims to supersede completely the traditional tissue replacement by implants or by pharmaceutical therapies. Rather, lessons have been learnt from the development of traditional implants and drugs which can now be integrated in the development of new strategies for regenerative medicine.

This chapter summarizes the principal aspects of...


Tissue Engineering Hepatocyte Growth Factor Tissue Regeneration Regenerative Medicine Compound Annual Growth Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The author is grateful to Mr. Mike Helias for its scanning electron microscopy technical support and to Dr. Steve Meikle for providing the chemical structures.


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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.School of Pharmacy & Biomolecular SciencesUniversity of BrightonBrighton BN2 4GJUK

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