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Clinical Applications of Bone Tissue Engineering

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Strategies in Regenerative Medicine

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Authors and Affiliations

  1. Advanced Biotechnology Center, Genova, Italy; Department of Communication, Computer and System Sciences, University of Genova, Italy

    Silvia Scaglione

Authors
  1. Silvia Scaglione
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  2. Rodolfo Quarto
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Corresponding author

Correspondence to Silvia Scaglione .

Editor information

Editors and Affiliations

  1. School of Pharmacy &, Biomolecular Sciences, University of Brighton, Lewes Road, Brighton, BN2 4GJ, United Kingdom

    Matteo Santin

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Questions/Exercises

  1. 1.

    Can the chemical composition of the scaffolds influence the cell adhesion mechanisms?

  2. 2.

    Which parameters may influence the vascularization process of the implanted graft?

  3. 3.

    Which scaffold parameter should be well controlled during its planning and development?

  4. 4.

    Which is the best porosity of engineered grafts able to guarantee an efficient in vivo bone formation?

  5. 5.

    Can suitable mechanical properties requirements influence the choice of the scaffold to be implanted, in terms of its chemical composition?

  6. 6.

    Which parameters may influence the in vivo degradation process of the implanted graft?

  7. 7.

    Can the internal architecture of the scaffolds influence the cell migration mechanisms and the in vivo matrix deposition kinetic?

  8. 8.

    Can different clinical settings (maxillo-facial, orthopedic surgery, etc.) influence the choice of the bone graft to be implanted?

  9. 9.

    Can bone defect size influence the choice of the bone graft to be implanted, in terms of its chemical composition and/or internal architecture?

  10. 10.

    Has the use of osteogenic stem cells still displayed some limitations for their wide use to regenerate skeletal tissues?

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Scaglione, S., Quarto, R. (2009). Clinical Applications of Bone Tissue Engineering. In: Santin, M. (eds) Strategies in Regenerative Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-74660-9_15

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