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Therapeutic Strategies in Ocular Tissue Regeneration: The Role of Stem Cells

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Author information

Authors and Affiliations

  1. Tennent Institute of Ophthalmology Gartnavel General Hospital, Glasgow, Scotland, UK

    K. Ramaesh

Authors
  1. K. Ramaesh
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  2. N. Stone
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  3. B. Dhillon
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Editor information

Editors and Affiliations

  1. School of Pharmacy &, Biomolecular Sciences, University of Brighton, Lewes Road, Brighton, BN2 4GJ, United Kingdom

    Matteo Santin

Additional information

Questions/Exercises

  1. 1.

    Explain the role played by the main eye component in the vision process

  2. 2.

    List the main locations of stem cells in eye tissues.

  3. 3.

    Give an example of a major eye pathology and discuss its mechanism.

  4. 4.

    What is the cell biology mechanisms linking inflammatory response to cell transdifferentiation?

  5. 5.

    Describe the role of corneal epithelium in the tissue regeneration.

  6. 6.

    Critically discuss the treatments to prevent ocular tissue damages in the light of inflammatory response and tissue remodeling biochemistry.

  7. 7.

    What are the main limbal transplantation methods and which is the role played by stem cells in their clinical efficacy?

  8. 8.

    Which are the main substrates for ex vivo limbal cell expansion? Why these substrates are preferred for this process?

  9. 9.

    Describe the main clinical treatments for macula degeneration and compare their efficacy.

  10. 10.

    Critically discuss the main strategies for eye gene therapy.

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Ramaesh, K., Stone, N., Dhillon, B. (2009). Therapeutic Strategies in Ocular Tissue Regeneration: The Role of Stem Cells. In: Santin, M. (eds) Strategies in Regenerative Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-74660-9_11

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