Colon biopsies are most often performed for one of three reasons:

  1. 1.

    To evaluate a polyp or mass

  2. 2.

    To study a patient with inflammatory bowel disease and monitor dysplasia

  3. 3.

    To look for an explanation for diarrhea


The history is very important; you should not be diagnosing a tubular adenoma when the endoscopist did not see a polyp. You may also be missing a more ominous diagnosis (discussed later). Assuming that you have at least a succinct history or description from the endoscopist, therefore, your approach to the biopsy depends on what you are looking for.


Inflammatory Bowel Disease Lamina Propria Paneth Cell Hyperplastic Polyp Medullary Carcinoma 


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© Springer Science+Business Media, LLC 2008

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