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Alterations in Cortical GABA Neurotransmission in Schizophrenia: Causes and Consequences

  • David A. Lewis
  • Takanori Hashimoto
  • Jaime G. Maldonado-Aviles
  • Harvey Morris

Schizophrenia is frequently noted to be a heterogeneous disorder, at both the levels of etiological risk factors and clinical manifestations. The extent to which this heterogeneity reflects variability (variance of a particular parameter within a class) and diversity (the existence of different classes within a population) remains to be determined. As demonstrated by the other volumes in this book, multiple molecular, cellular and circuitry candidates could contribute to this heterogeneity.

Keywords

Pyramidal Neuron Axon Initial Segment Gaba Neuron Cereb Cortex Gaba Neurotransmission 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • David A. Lewis
    • 1
  • Takanori Hashimoto
    • 1
  • Jaime G. Maldonado-Aviles
    • 1
  • Harvey Morris
    • 1
  1. 1.Department of PsychiatryUniversity of PittsburghPittsburghUSA

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