Abstract
Based on animal models, we specify the major role of different bioactive milk components known to participate significantly in neonatal health promotion and in protection against a large number of infectious diseases and the development of allergies and asthma.
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References
Aberg, N., Engstrom, I.,&Lindberg, U. (1989). Allergic diseases in Swedish school children. Acta Paediatrica Scandinavica, 78(2), 246–252.
Almqvist, C., Pershagen, G.,&Wickman, M. (2005). Low socioeconomic status as a risk factor for asthma, rhinitis and sensitization at 4 years in a birth cohort. Clinical and Experimental Allergy, 355), 612–618.
Arifeen, S., Black, R. E., Antelman, G., Baqui, A., Caulfield, L.,&Becker, S. (2001). Exclusive breastfeeding reduces acute respiratory infection and diarrhea deaths among infants in Dhaka slums. Pediatrics, 108(4), E67.
Arshad, S. H., Tariq, S. M., Matthews, S.,&Hakim, E. (2001). Sensitization to common allergens and its association with allergic disorders at age 4 years: A whole population birth cohort study. Pediatrics, 108(2), E33.
Baldi, A., Savoini, G., Cheli, F., Fantuz, F., Senatore, E., Bertocci, L.,&Politis, I. (1996). Changes in plasmin-plasminogen-plasminogen activator system in milk from Italian Fresian herds. International Dairy Journal, 6, 1045–1053.
Baldi, A., Politis, I., Pecorini, C., Fusi, E., Chronopoulou, R.,&Dell'Orto, V. (2005). Biological effects of milk proteins and their peptides with emphasis on those related to the gastrointestinal ecosystem. Journal of Dairy Research, 72 (Spec No.), 66–72.
Balmer, S. E.,&Wharton, B. A. (1989). Diet and faecal flora in the newborn: Breast milk and infant formula. Archives of Disease in Childhood, 64, 1672.
Batish, V. K., Chander, H., Zumdegeni, K. C., Bhatta, K. L.,&Singh, R. S. (1988). Antibacterial activity of lactoferrin against some common food-borne pathogenic organisms. Australian Journal of Dairy Technology, 5, 16–18.
Baylis, J. M., Leeds, A. R.,&Challacombe, D. N. (1983). Persistent nausea and food aversions in pregnancy. A possible association with cow's milk allergy in infants. Clinical Allergy, 13(3), 263–269.
Becker, A. B. (2005). Primary prevention of allergy and asthma is possible. Clinical Reviews in Allergy and Immunology, 28(1), 5–16.
Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., Kawase, K.,&Tomita, M. (1992). Identification of the bactericidal domain of lactoferrin. Biochimica et Biophysica Acta, 1121, 130–136.
Bottcher, M. F., Jenmalm, M. C.,&Bjorksten, B. (2003). Cytokine, chemokine and secretory IgA levels in human milk in relation to atopic disease and IgA production in infants. Pediatric Allergy and Immunology, 14(1), 35–41.
Bruno, G., Milita, O., Ferrara, M., Nisini, R., Cantani, A.,&Businco, L. (1993). Prevention of atopic diseases in high risk babies (long-term follow-up). Allergy Proceedings, 14(3), 181–186; discussion 186–187.
Burr, M. L., Limb, E. S., Maguire, M. J., Amarah, L., Eldridge, B. A., Layzell, J. C.,&Merrett, T. G. (1993). Infant feeding, wheezing, and allergy: A prospective study. Archives of Disease in Childhood, 68(6), 724–728.
Businco, L., Marchetti, F., Pellegrini, G., Cantani, A.,&Perlini, R. (1983). Prevention of atopic disease in "at-risk newborns" by prolonged breast-feeding. Annals of Allergy, 51 (2 Pt 2), 296–299.
Butland, B. K., Strachan, D. P., Lewis, S., Bynner, J., Butler, N.,&Britton, J. (1997). Investigation into the increase in hay fever and eczema at age 16 observed between the 1958 and 1970 British birth cohorts. British Medical Journal, 315(7110), 717–721.
Chan-Yeung, M., Manfreda, J., Dimich-Ward, H., Ferguson, A., Watson, W.,&Becker, A. (2000). A randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants. Archives of Pediatrics&Adolescent Medicine, 154(7), 657–663.
Chandra, R. K. (1997). Five-year follow-up of high-risk infants with family history of allergy who were exclusively breast-fed or fed partial whey hydrolysate, soy, and conventional cow's milk formulas. Journal of Pediatric Gastroenterology and Nutrition, 24(4), 380–388.
Chandra, R. K. (2000). Food allergy and nutrition in early life: Implications for later health. Proceedings of the Nutrition Society, 59(2), 273–277.
Chandra, R. K., Singh, G.,&Shridhara, B. (1989). Effect of feeding whey hydrolysate, soy and conventional cow milk formulas on incidence of atopic disease in high risk infants. Annals of Allergy, 63(2), 102–106.
Chien, P. F.,&Howie, P. W. (2001). Breast milk and the risk of opportunistic infection in infancy in industrialised and non-industrialised settings. Advances in Nutritional Research, 10, 69–104.
Chulada, P. C., Arbes, S. J., Jr., Dunson, D.,&Zeldin, D. C. (2003). Breast-feeding and the prevalence of asthma and wheeze in children: Analyses from the Third National Health and Nutrition Examination Survey, 1988–1994. Journal of Allergy and Clinical Immunology, 111(2), 328–336.
Clare, D. A.,&Swaisgood, H. E. (2000). Bioactive milk peptides: A prospectus. Journal of Dairy Science, 83, 1187–1195.
Cogswell, J. J., Mitchell, E. B.,&Alexander, J. (1987). Parental smoking, breast feeding, and respiratory infection in development of allergic diseases. Archives of Disease in Childhood, 62(4), 338–344.
Dionysius, D. A., Grieve, P. A.,&Milne, J. M. (1993). Forms of lactoferrin: Their antibacterial effect on enterotoxigenic Escherichia coli. Journal of Dairy Science, 76, 2597–2606.
Douglass, J. A.,&O'Hehir, R. E. (2006). Diagnosis, treatment and prevention of allergic disease: The basics. The Medical Journal of Australia, 185(4), 228–233.
Duchen, K., Casas, R., Fageras-Bottcher, M., Yu, G.,&Bjorksten, B. (2000). Human milk polyunsaturated long-chain fatty acids and secretory immunoglobulin A antibodies and early childhood allergy. Pediatric Allergy and Immunology, 11(1), 29–39.
Epton, M. J., Town, G. I., Ingham, T., Wickens, K., Fishwick, D., Crane, J.,&NZA2CS (2007). The New Zealand Asthma and Allergy Cohort Study (NZA2CS): Assembly, demographics and investigations. BMC Public Health, 7, 26.
Exner, H.,&Greinecker, G. (1996). [Prevention of allergy.] Wiener medizinishe Wochenschrift 1946, 146(15), 406–411.
Fantuz, F., Polidori, F., Cheli, F.,&Baldi, A. (2001). Plasminogen activation system in goat milk and its relation with composition and coagulation properties. Journal of Dairy Science, 84, 1786–1790.
Field, C. J. (2005). The immunological components of human milk and their effect on immune development in infants. Journal of Nutrition, 135, 1–4.
Fiocchi, A., Borella, E., Di Donna, C., Lista, G. L., Turrini, D.,&Riva, E. (1984). [Respiratory atopy and season of birth: Epidemiologic considerations.] La Pediatria Medica e Chirurgica, 6(5), 673–676.
Forsyth, B. W., McCarthy, P. L.,&Leventhal, J. M. (1985). Problems of early infancy, formula changes, and mothers' beliefs about their infants. Journal of Pediatrics, 106(6), 1012–1017.
Golding, J., Emmett, P. M.,&Rogers, I. S. (1997). Does breast feeding have any impact on non-infectious, non-allergic disorders? Early Human Development, 49 (Suppl), S131–142.
Gruskay, F. L. (1982). Comparison of breast, cow, and soy feedings in the prevention of onset of allergic disease: A 15-year prospective study. Clinical Pediatrics, 21(8), 486–491.
Habbick, B. F., Pizzichini, M. M., Taylor, B., Rennie, D., Senthilselvan, A.,&Sears, M. R. (1999). Prevalence of asthma, rhinitis and eczema among children in 2 Canadian cities: The International Study of Asthma and Allergies in Childhood. Canadian Medical Association Journal, 160(13), 1824–1828.
Halken, S. (2003). Early sensitisation and development of allergic airway disease—Risk factors and predictors. Paediatric Respiratory Reviews, 4(2), 128–134.
Halken, S. (2004). Prevention of allergic disease in childhood: Clinical and epidemiological aspects of primary and secondary allergy prevention. Pediatric Allergy and Immunology, 15 (Suppl 16), 4–5, 9–32.
Haque, M. F., Hussain, M., Sarkar, A., Hoque, M. M., Ara, F. A.,&Sultana, S. (2002). Breast-feeding counselling and its effect on the prevalence of exclusive breast-feeding. Journal of Health, Population, and Nutrition, 20(4), 312–316.
Harris, J. M., Cullinan, P., Williams, H. C., Mills, P., Moffat, S., White, C.,&Newman Taylor, A. J. (2001). Environmental associations with eczema in early life. British Journal of Dermatology, 144(4), 795–802.
Hill, H. S., Doull, F., Rutherford, K. J.,&Cross, M. L. (2000). Immunoregulatory peptides in bovine milk. British Journal of Nutrition, 84 (Suppl 1), S111–S117.
Hoek, K. S., Milne, J. M., Grieve, P. A., Dionysius, D. A.,&Smith, R. (1997). Antibacterial activity of bovine lactoferrin-derived peptides. Antimicrobial Agents and Chemotherapy, 41, 54–59.
Hoppu, U., Kalliomaki, M., Laiho, K.,&Isolauri, E. (2001). Breast milk—Immunomodulatory signals against allergic diseases. Allergy, 56 (Suppl 67), 23–26.
Isaacs, C. E. (2005). Human milk inactivates pathogens individually, additively and synergistically. Journal of Nutrition, 135(135), 1286–1288.
Isaacs, C. E., Kashyap, S., Heird, W. C.,&Thormar, H. (1990). Antiviral and antibacterial lipids in human milk and infant formula feeds. Archives of Disease in Childhood, 65, 861–864.
Kannan, S., Carruth, B. R.,&Skinner, J. (1999). Infant feeding practices of Anglo American and Asian Indian American mothers. Journal of the American College of Nutrition, 18(3), 279–286.
Kemp, A.,&Kakakios, A. (2004). Asthma prevention: Breast is best? Journal of Paediatrics and Child Health, 40(7), 337–339.
Kim, W. S., Ohashi, M., Tanaka, T., Kumura, H., Kim, G. Y., Kwon, I. K., Goh, J. S.,&Shimazaki, K. (2004). Growth-promoting effects of lactoferrin on L. acidophilus and Bifidobacterium spp. Biometals, 17, 279–283.
Kjellman, N. I.,&Nilsson, L. (1999). Is allergy prevention realistic and beneficial? Pediatric Allergy and Immunology, 10(12 Suppl), 11–17.
Kramer, M. S. (1988). Does breast feeding help protect against atopic disease? Biology, methodology, and a golden jubilee of controversy. Journal of Pediatrics, 112(2), 181–190.
Kull, I., Wickman, M., Lilja, G., Nordvall, S. L.,&Pershagen, G. (2002). Breast feeding and allergic diseases in infants—A prospective birth cohort study. Archives of Disease in Childhood, 87(6), 478–481.
Kummeling, I., Thijs, C., Penders, J., Snijders, B. E., Stelma, F., Reimerink, J., Koopmans, M., Dagnelie, P. C., Huber, M., Jansen, M. C., de Bie, R.,&van den Brandt, P. A. (2005). Etiology of atopy in infancy: The KOALA Birth Cohort Study. Pediatric Allergy and Immunology, 16(8), 679–684.
Kummeling, I., Stelma, F. F., Dagnelie, P. C., Snijders, B. E., Penders, J., Huber, M., van Ree, R., van den Brandt, P. A.,&Thijs, C. (2007). Early life exposure to antibiotics and the subsequent development of eczema, wheeze, and allergic sensitization in the first 2 years of life: The KOALA Birth Cohort Study. Pediatrics, 119(1), e225–e231.
Kurukulaaratchy, R. J., Matthews, S.,&Arshad, S. H. (2006). Relationship between childhood atopy and wheeze: What mediates wheezing in atopic phenotypes? Annals of Allergy, Asthma and Immunology, 97(1), 84–91.
Li, E. W.,&Mine, Y. (2004). Immunoenhancing effects of bovine glycomacropeptide and its derivatives on the proliferative response and phagocytic activity of human macrophage-like cells, U937. Journal of Agricultural Food Chemistry, 52, 2704–2708.
Liepke, C., Adermann, K., Raida, M., Mägert, H. J., Forssmann, W. G.,&Zucht, H. D. (2002). Human milk provides peptides highly stimulating the growth of bifidobacteria. European Journal of Biochemistry, 269, 712–718.
Lönnerdal, B. (2000). Breast milk: A truly functional food. Nutrition, 16, 509–511.
Lönnerdal, B. (2003). Nutritional and physiologic significance of human milk proteins. American Journal of Clinical Nutrition, 77, 1537S–1543S.
Marks, G. B., Mihrshahi, S., Kemp, A. S., Tovey, E. R., Webb, K., Almqvist, C., Ampon, R. D., Crisafulli, D., Belousova, E. G., Mellis, C. M., Peat, J. K.,&Leeder, S. R. (2006). Prevention of asthma during the first 5 years of life: A randomized controlled trial. Journal of Allergy and Clinical Immunology, 118(1), 53–61.
Martinez, F. D. (2007). Gene-environment interactions in asthma: With apologies to William of Ockham. Proceedings of the American Thoracic Society, 4(1), 26–31.
McGeady, S. J. (2004). Immunocompetence and allergy. Pediatrics, 113(4 Suppl), 1107–1113.
Meisel, H. (1997). Biochemical properties of bioactive peptides derived from milk proteins: Potential nutraceuticals for food and pharmaceutical applications. Livestock Production Science, 50, 125–138.
Nafstad, P., Nystad, W.,&Jaakkola, J. J. (2002). The use of a feather quilt, childhood asthma and allergic rhinitis: A prospective cohort study. Clinical and Experimental Allergy, 32(8), 1150–1154.
Newburg, D. S. (1996). Oligosaccharides and glycoconjugates in human milk: Their role in host defence. Journal of Mammary Gland Biology and Neoplasia, 1, 271–283.
Newburg, D. S. (2005). Innate immunity and human milk. Journal of Nutrition, 135, 1308–1312.
Oddy, W. H., Sherriff, J. L., de Klerk, N. H., Kendall, G. E., Sly, P. D., Beilin, L. J., Blake, K. B., Landau, L. I.,&Stanley, F. J. (2004). The relation of breastfeeding and body mass index to asthma and atopy in children: A prospective cohort study to age 6 years. American Journal of Public Health, 94(9), 1531–1537.
Oram, J. D.,&Reiter, B. (1968). Inhibition of bacteria by lactoferrin and other iron-chelating agents. Biochimica et Biophysica Acta, 170, 351–365.
Payne, K., Davidson, P. M.,&Oliver, S. P. (1990). Influence of bovine lactoferrin on the growth of Listeria monocytogenes. Journal of Food Protection, 53, 468–472.
Pecorini, C., Martino, P., Reggi, S., Fogher, C.,&Baldi, A. (2003). Evaluation of biological effects of recombinant porcine lactoferrin expressed in Pichia pastoris yeast. Proceedings of the 6th International Conference on Lactoferrin: Structure, Function and Applications, Capri, Italy p70.
Pecorini, C., Savazzini, F., Martino, P. A., Fusi, E., Fogher, C.,&Baldi, A. (2005). Heterologous expression of biologically active porcine lactoferrin in Pichia pastoris yeast. Veterinary Research Communications, 29 (Suppl 2), 379–382.
Pecquet, S., Bovetto, L., Maynard, F.,&Fritsche, R. (2000). Peptides obtained by tryptic hydrolysis of bovine β-lactoglobulin induce specific oral tolerance in mice. Journal of Allergy and Clinical Immunology, 105, 514–521.
Penders, J., Thijs, C., van den Brandt, P. A., Kummeling, I., Snijders, B., Stelma, F., Adams, H., van Ree, R.,&Stobberingh, E. E. (2007). Gut microbiota composition and development of atopic manifestations in infancy: The KOALA birth cohort study. Gut 56 (5), 661–667.
Politis, I. (1996). Plasminogen activator system: Implications for mammary cell growth and involution. Journal of Dairy Science, 79, 1097–1107.
Politis, I., Voudouri, A., Bizelis, I.,&Zervas, G. (2003). The effect of various vitamin E derivatives on the urokinase-plasminogen activator system of ovine macrophages and neutrophils. British Journal of Nutrition, 89, 259–265.
Prescott, S. L. (2003). Early origins of allergic disease: A review of processes and influences during early immune development. Current Opinion in Allergy and Clinical Immunology, 3(2), 125–132.
Prescott, S. L.,&Tang, M. L. (2005). The Australasian Society of Clinical Immunology and Allergy position statement: Summary of allergy prevention in children. Medical Journal of Australia, 182(9), 464–467.
Prioult, G., Pecquet, S.,&Fliss, I. (2004). Stimulation of interleukin-10 production by acidic β-lactoglobulin-derived peptides hydrolyzed with Lactobacillus paracasei NCC2461 peptidases. Clinical and Diagnostic Laboratory Immunology, 11, 266–271.
Radon, K.,&Schulze, A. (2006). Adult obesity, farm childhood, and their effect on allergic sensitization. Journal of Allergy and Clinical Immunology, 118(6), 1279–1283.
Reilly, J. J.,&Wells, J. C. (2005). Duration of exclusive breast-feeding: Introduction of complementary feeding may be necessary before 6 months of age. British Journal of Nutrition, 94(6), 869–872.
Rigotti, E., Piacentini, G. L., Ress, M., Pigozzi, R., Boner, A. L.,&Peroni, D. G. (2006). Transforming growth factor-beta and interleukin-10 in breast milk and development of atopic diseases in infants. Clinical and Experimental Allergy, 36(5), 614–618.
Sausenthaler, S., Koletzko, S., Schaaf, B., Lehmann, I., Borte, M., Herbarth, O., von Berg, A., Wichmann, H. E., Heinrich, J., the LISA Study Group (2007). Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age. American Journal of Clinical Nutrition, 85(2), 530–537.
Schanbacher, F. L., Talhouk, R. S.,&Murray, F. A. (1997). Biology and origin of bioactive peptides in milk. Livestock Production Science, 50, 105–123.
Schanbacher, F. L., Talhouk, R. S., Murray, F. A., Gherman, L. I.,&Willett, L. B. (1998). Milk-borne bioactive peptides. International Dairy Journal, 8, 393–403.
Sears, M. R., Greene, J. M., Willan, A. R., Taylor, D. R., Flannery, E. M., Cowan, J. O., Herbison, G. P.,&Poulton, R. (2002). Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: A longitudinal study. Lancet, 360(9337), 901–907.
Snijders, B. E., Damoiseaux, J. G., Penders, J., Kummeling, I., Stelma, F. F., van Ree, R., van den Brandt, P. A.,&Thijs, C. (2006). Cytokines and soluble CD14 in breast milk in relation with atopic manifestations in mother and infant (KOALA Study). Clinical and Experimental Allergy, 36(12), 1609–1615.
Snijders, B. E., Thijs, C., Kummeling, I., Penders, J.,&van den Brandt, P. A. (2007). Breastfeeding and infant eczema in the first year of life in the KOALA birth cohort study: A risk period-specific analysis. Pediatrics, 119(1), e137–e141.
Stoney, R. M., Woods, R. K., Hosking, C. S., Hill, D. J., Abramson, M. J.,&Thien, F. C. (2004). Maternal breast milk long-chain n-3 fatty acids are associated with increased risk of atopy in breastfed infants. Clinical and Experimental Allergy, 34(2), 194–200.
Sugiyama, M., Arakawa, H., Ozawa, K., Mizuno, T., Mochizuki, H., Tokuyama, K.,&Morikawa, A. (2007). Early-life risk factors for occurrence of atopic dermatitis during the first year. Pediatrics, 119(3), e716–e723.
Sunyer, J., Torrent, M., Muñoz-Ortiz, L., Ribas-Fitó, N., Carrizo, D., Grimalt, J., Antó, J. M.,&Cullinan, P. (2005). Prenatal dichlorodiphenyldichloroethylene (DDE) and asthma in children. Environmental Health Perspectives, 113(12), 1787–1790.
Sunyer, J., Jarvis, D., Gotschi, T., Garcia-Esteban, R., Jacquemin, B., Aguilera, I., Ackerman, U., de Marco, R., Forsberg, B., Gislason, T., Heinrich, J., Norbäck, D., Villani, S.,&Künzli, N. (2006a). Chronic bronchitis and urban air pollution in an international study. Occupational and Environmental Medicine, 63(12), 836–843.
Sunyer, J., Torrent, M., Garcia-Esteban, R., Ribas-Fitó, N., Carrizo, D., Romieu, I., Antó, J. M.,&Grimalt, J. O. (2006b). Early exposure to dichlorodiphenyldichloroethylene, breastfeeding and asthma at age six. Clinical and Experimental Allergy, 36(10), 1236–1241.
Sutas, Y., Soppi, E., Korhonen, H., Syvaoja, E. L., Saxelin, M., Rokka, T.,&Isolauri, E. (1996). Suppression of lymphocyte proliferation in in vitro bovine casein hydrolyzed with Lactobacillus casei GG-derived enzymes. Journal of Allergy and Clinical Immunology, 98, 216–224.
Telemo, E.,&Hanson, L. A. (1996). Antibodies in milk. Journal of Mammary Gland Biology and Neoplasia, 1, 243–249.
Teraguchi, S., Shin, K., Ozawa, K., Nakamura, S., Fukuwatari, Y., Tsuyuri, S., Namihira, H.,&Shimanura, S. (1995). Bacteriostatic effect of orally administered bovine lactoferrin on proliferation of Clostridium species in the gut of mice fed bovine milk. Applied and Environmental Microbiology, 61, 501–506.
Thestrup-Pedersen, K. (2003). Atopic eczema. What has caused the epidemic in industrialised countries and can early intervention modify the natural history of atopic eczema? Journal of Cosmetic Dermatology, 2(3–4), 202–210.
Van der Kraan, M. I. A., Groenink, J., Nazmi, K., Veerman, E. C. I., Bolscher, J. G. M.,&Amerongen, A. V. N. (2004). Lactoferrampin: A novel antimicrobial peptide in the N1-domain of bovine lactoferrin. Peptides, 25, 177–183.
Van Leeuwen, P., Oosting, S. J., Mouwen, J.,&Verstegen, M. W. A. (2000). Effects of a lactoperoxidase system and lactoferrin, added to a milk replacer diet, on severity of diarrhoea, intestinal morphology and microbiology of digesta and faeces in young calves. Journal of Animal Physiology and Animal Nutrition, 83, 15–23.
van Odijk, J., Kull, I., Borres, M. P., Brandtzaeg, P., Edberg, U., Hanson, L. A., Host, A., Kuitunen, M., Olsen, S. F., Skerfving, S., Sundell, J.,&Wille, S. (2003). Breastfeeding and allergic disease: A multidisciplinary review of the literature (1966–2001) on the mode of early feeding in infancy and its impact on later atopic manifestations. Allergy, 58(9), 833–843.
Wilson, A. C., Forsyth, J. S., Greene, S. A., Irvine, L., Hau, C.,&Howie, P. W. (1998). Relation of infant diet to childhood health: Seven year follow up of cohort of children in Dundee infant feeding study. British Medical Journal, 316(7124), 21–25.
Wilson, W. H. (1983). Recurrent acute otitis media in infants—Role of immune complexes acquired in utero. Laryngoscope, 93(4), 418–421.
Wjst, M., Dharmage, S., André, E., Norback, D., Raherison, C., Villani, S., Manfreda, J., Sunyer, J., Jarvis, D., Burney, P.,&Svanes, C. (2005). Latitude, birth date, and allergy. PLoS Medicine, 2(10), e294.
Woodcock, A., Lowe, L. A., Murray, C. S., Simpson, B. M., Pipis, S. D., Kissen, P., Simpson, A., Custovic, A.,&NMAaAS Group (2004). Early life environmental control: Effect on symptoms, sensitization, and lung function at age 3 years. American Journal of Respiratory and Critical Care Medicine, 170(4), 433–439.
Zacharasiewicz, A., Zidek, T., Haidinger, G., Waldhor, T., Suess, G.,&Vutuc, C. (1999). Indoor factors and their association to respiratory symptoms suggestive of asthma in Austrian children aged 6–9 years. Wien Klin Wochenschr, 111(21), 882–886.
Zieger, R. S., Heller, S., Mellon, M. H., Forsythe, A. B., O'Connor, R. D., Hamburger, R. N.&Schatz, M. (1989). Effect of combined maternal and infant food-allergen avoidance on development of atopy in early infancy a randomized study. Journal of Allergy and Clinical Immunology, 84(1), 72–89.
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Rosetta, L., Baldi, A. (2008). On the Role of Breastfeeding in Health Promotion and the Prevention of Allergic Diseases. In: Bösze, Z. (eds) Bioactive Components of Milk. Advances in Experimental Medicine and Biology, vol 606. Springer, New York, NY. https://doi.org/10.1007/978-0-387-74087-4_19
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