Scent, Mate Choice and Genetic Heterozygosity
Females of many species choose to mate with relatively unrelated males in order to ensure outbred, heterozygous offspring. There is some evidence to suggest that the MHC is involved in mate choice decisions, either because MHC heterozygous offspring are more resistant to disease, or because the highly detectable odours associated with this region allow it to act as a marker of general inbreeding. To determine which role the MHC plays it is necessary to disentangle this region from the genetic background, a requirement which has generally proven difficult to achieve. We argue that the emphasis on MHC’s role in mate choice has resulted in other potential markers of inbreeding being neglected, and discuss the evidence for MHC disassortative mating, the interaction with genetic background, and a possible role for alternative markers of inbreeding.
KeywordsMajor Histocompatibility Complex Mate Choice House Mouse Major Histocompatibility Complex Allele Genetic Compatibility
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- Aeschlimann, P.B., Häberli, M.A., Reusch, T.B.H., Boehm, T. and Milinski, M. (2003) Female sticklebacks Gasterosteus aculeatus use self-reference to optimize MHC allele number during mate selection. Behav. Ecol. Sociobiol. 54, 119–126.Google Scholar
- Cheetham, S.A., Thom, M.D., Jury, F., Ollier, W.E.R., Beynon, R.J. and Hurst, J.L. (2007) MUPs not MHC provide a specific signal for individual recognition in wild house mice. Unpublished manuscript.Google Scholar
- Parrott, M.L., Ward, S.J. and Temple-Smith, P.D. (2007) Olfactory cues, genetic relatedness and female mate choice in the agile antechinus (Antechinus agilis). Behav. Ecol. Sociobiol., DOI:10.1007/s00265-006-0340-8.Google Scholar
- Rauch, R., Kalbe, M. and Reusch, T.B.H. (2006) Relative importance of MHC and genetic background for parasite load in a field experiment. Evol. Ecol. Res. 8, 373–386.Google Scholar
- Schellinck, H.M., Slotnick, B.M. and Brown, R.E. (1997) Odors of individuality originating from the major histocompatibility complex are masked by diet cues in the urine of rats. Anim. Learn. Behav. 25, 193–199.Google Scholar
- Sherborne, A.L., Thom, M.D., Paterson, S., Jury, F., Ollier, W.E.R., Stockley, P., Beynon, R.J. and Hurst, J.L. (2007) The molecular basis of inbreeding avoidance in house mice. Submitted.Google Scholar