Pericytes were first described by Rouget in 1873 and since then much has been speculated on their nature and role(s). They are located between the inner and outer vascular basement membrane of arterioles, capillaries, and venules, and are thus part of the vascular wall. In standard hematoxylin-eosin or Nissl-stained sections, pericytes are difficult to recognize, but they can be identified under the electron microscope and in semithin sections, where the vascular basement membranes are visible. Moreover several antibodies demark their unique morphology and therefore, allow clear-cut identification at the light microscopic level.
KeywordsExperimental Autoimmune Encephalomyelitis Platelet Derive Growth Factor Perivascular Space Cereb Blood Flow Perivascular Cell
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