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Waldenstrom's Macrogloblinemia/ Lymphoplasmacytic Lymphoma

  • Steven P. Treon
  • Evdoxia Hatjiharissi
  • Giampaolo Merlini

Waldenström’s macroglobulinemia (WM) is a distinct clinicopathological entity resulting from the accumulation, predominantly in the bone marrow, of clonally related lymphocytes, lymphoplasmacytic cells, and plasma cells that secrete a monoclonal IgM protein (Figure 9.1) (1). This condition is considered to correspond to the lymphoplasmacytic lymphoma (LPL) as defined by the Revised European American Lymphoma (REAL) and World Health Organization (WHO) classification systems (2, 3). Most cases of LPL are WM, with less than 5% of cases made up of IgA, IgG, and nonsecreting LPL.

Keywords

Multiple Myeloma Clin Oncol Nucleoside Analogue Cold Agglutinin Lymphoplasmacytic Lymphoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Steven P. Treon
    • 1
  • Evdoxia Hatjiharissi
    • 1
  • Giampaolo Merlini
    • 2
  1. 1.Dana Farber Cancer InstituteBostonUSA
  2. 2.Fondazione IRCCS Policlinico San Matteo and Department of BiochemistryUniversity of PaviaItaly

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