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Hairy Cell Leukemia

  • Paul Timothy Fanta
  • Alan Saven

Hairy cell leukemia (HCL) is a rare, chronic, B-cell lymphoproliferative disorder with well-defined diagnostic criteria and successful treatment outcomes. HCL, classified as an indolent non-Hodgkin’s lymphoma in the World Health Organization (WHO) classification, typically presents with the diagnostic triad of pancytopenia, splenomegaly, and circulating cells with characteristic cytoplasmic villous projections. In this chapter, we will review insights pertaining to the historical aspects, epidemiology, pathogenesis, biology, clinical presentation, diagnosis, and treatments of this uncommon but fascinating hematologic entity.

Keywords

Clin Oncol Chronic Lymphocytic Leukemia Minimal Residual Disease Hairy Cell Leukemia Hairy Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Paul Timothy Fanta
    • 1
  • Alan Saven
    • 1
  1. 1.Scripps ClinicLa JollaUSA

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