The Retrotrapezoid Nucleus and Central Chemoreception
Central respiratory chemoreception (CRC) is the mechanism by which brain pCO2 regulates breathing. The molecular and cellular basis of CRC is still poorly understood. In this review, we describe the properties of a cluster of pH-responsive neurons located in the retrotrapezoid region of the medulla oblongata and analyze whether these cells qualify as central respiratory chemoreceptors.
KeywordsVentrolateral Medulla Peripheral Chemoreceptor Solitary Tract Nucleus Central Chemoreception Central Chemosensitivity
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