Evidence-Based Treatments for Adolescent Substance Use Disorders

  • Deborah Deas
  • Kevin Gray
  • Himanshu Upadhyaya
Part of the Issues in Clinical Child Psychology book series (ICCP)


Family Therapy Substance Abuse Treatment Adolescent Substance Adolescent Smoker Bupropion Sustained Release 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Aarons, G. A., Brown, S. A., Coe, M. T., Myers, M. G., Garland, A. F., Ezzert-Lofstraum, R., et al. (1999). Adolescent alcohol and drug abuse and health. Journal of Adolescent Health, 24, 412–421.PubMedCrossRefGoogle Scholar
  2. Azrin, N., Acierno, E., Kogan, B., Donohue, B., Besalel, V. A., & McMahon, P. T. (1996). Follow-up results of supportive versus behavioral therapy for illicit drug use. Behaviour Research and Therapy, 1(1), 41–46.CrossRefGoogle Scholar
  3. Azrin, N., Donohue, B., Besalel, V., et al. (1994). Youth drug abuse treatment: A controlled outcome study. Journal of Child and Adolescent Substance Abuse, 32, 857–866.Google Scholar
  4. Azrin, D., Donohue, B., Teichner, G., Crum, T., Howell, J., & DeCato, L. A. (2001). A controlled evaluation and description of individual-cognitive problem solving and family-behavior therapies in dually-diagnosed conduct-disordered and substance-dependent youth. Journal of Child and Adolescent Substance Abuse, 1(1), 1–43.CrossRefGoogle Scholar
  5. Barton, C., & Alexander, J. (1981). Functional family therapy. In A. Gurman & D. Kniskern (Eds.), Handbook of Family Therapy (pp. 403–443). New York: Brunner/Mazel.Google Scholar
  6. Brent, D. A. (1995). Risk factors for adolescent suicide and suicidal behavior: Mental and substance abuse disorders, family environmental factors, and life stress. Suicide Life-Threatening Behavior, 25, 52–63.Google Scholar
  7. Budney, A. G., & Higgins, S. T. (1998). Therapy Manuals for Drug Addiction: A Community Reinforcement Plus Voucher Approach for Treating Cocaine Addiction. Rockville, MD: National Institute on Drug Abuse.Google Scholar
  8. Catalano, R. F., Hawkins, J. D., Wells, E. A., Miller, J., & Brewer, D. (1990). Evaluation of the effectiveness of adolescent drug abuse treatment, assessment of risks for relapse, and promising approaches for relapse prevention. The International Journal of the Addictions, 25, 1085–1140.PubMedGoogle Scholar
  9. Center for Substance Abuse Treatment (2004). Clinical guidelines for the use of buprenorphine in the treatment of opioid addiction. Treatment Improvement Protocol (TIP) Series 40. [DHHS Publication No. (SMA) 04-3939]. Rockville, MD: Substance Abuse and Mental Health Services Administration. Retrieved December 9, 2006, from Scholar
  10. Coatsworth, J. D., Santisteban, D. A., McBride, C. K., & Szapocznik, J. (2001). Brief strategic family therapy versus community control: Engagement, retention, and an exploration of the role of adolescent symptom severity. Family Process, 3(3), 313–332.CrossRefGoogle Scholar
  11. Colby, S. M., Monti, P. M., Barnett, N. P., Rohsenow, D. J., Weissman, K., Spirito, A., et al. (1998). Brief motivational interviewing in a hospital setting for adolescent smoking: A preliminary study. Journal of Consulting and Clinical Psychology, 66, 574–578.PubMedCrossRefGoogle Scholar
  12. Collins, E. D., & Kleber, H. D. (2004). Opioids. In M. Galanter & H. D. Kleber (Eds.) Textbook of Substance Abuse Treatment (pp. 265–289). Washington, DC: American Psychiatric Publishing.Google Scholar
  13. Corby, E. A., Roll, J. M., Ledgerwood, D. M., & Schuster, C. R. (2000). Contingency management interventions of treating the substance abuse of adolescents: A feasibility study. Experimental and Clinical Psychopharmacology, 3(3), 371–376.CrossRefGoogle Scholar
  14. DeAngelis, G., & Lehmann, W. (1973). Adolescents and short-term, low-dose methadone maintenance. The International Journal of Addictions, 5(5), 853–863.Google Scholar
  15. Deas, D., Riggs, P., Langenbucher, M., & Brown, S. (2000). Adolescents are not adults: Developmental considerations in alcohol users. Alcoholism: Clinical and Experimental Research, 2(2), 232–237.CrossRefGoogle Scholar
  16. Deas, D., & Thomas, S. (2001). An overview of controlled studies of adolescent substance abuse treatment. The American Journal on Addictions, 10, 178–189.PubMedCrossRefGoogle Scholar
  17. Deas-Nesmith, D., Randall, C., Roberts, J., et al. (1998). Sertraline treatment of depressed adolescent alcoholics: A pilot study. Alcoholism: Clinical and Experimental Research, 22, 74A.Google Scholar
  18. Dennis, M., Godley, S. H., Diamond, G., Tims, F. M., Babor, T., Donaldson, J., et al. (2004). The cannabis youth treatment (CYT) study: Main findings from two randomized trials. Journal of Substance Abuse Treatment, 27, 197–213.PubMedCrossRefGoogle Scholar
  19. Elliott, L., Orr, L., Watson, L., & Jackson, A. (2005). Secondary prevention interventions for young drug users: A systematic review of the evidence. Adolescence, 157(157), 1–22.Google Scholar
  20. Friedman, A. (1989). Family therapy vs. parent groups: Effects on adolescent drug abusers. The American Journal of Family Therapy, 17, 335–347.CrossRefGoogle Scholar
  21. Geller, B., Cooper, T., Sun, K., Zimerman, B., Frazier, J., Williams, M., et al. (1998). A double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependence. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 171–178.PubMedCrossRefGoogle Scholar
  22. George, T. P., & O’Malley, S. S. (2004). Current pharmacological treatments for nicotine dependence. Trends in Pharmacological Sciences, 1(1), 42–48.CrossRefGoogle Scholar
  23. Hanson, K., Allen, S., Jensen, S., & Hatsukami, D. (2003). Treatment of adolescent smokers with the nicotine patch. Nicotine and Tobacco Research, 5, 515–526.PubMedCrossRefGoogle Scholar
  24. Henggeler, S. W., Clingempeel, W. G., Brondino, M. J., & Pickrel, S. G. (2002). Four-year follow-up of multisystemic therapy with substance-abusing and substance-dependent juvenile offenders. Journal of the American Academy of Child and Adolescent Psychiatry, 7(7), 868–874.CrossRefGoogle Scholar
  25. Henggeler, S. W., Pickrel, S. G., & Brondino, M. J. (1999). Multisystemic therapy of substance-abusing and dependent delinquents: Outcomes, treatment, fidelity, and transportability. Mental Health Services Research, 3(3), 171–184.CrossRefGoogle Scholar
  26. Henggeler, S. W., Schoenwald, S. K., Borduin, C. M., Rowland, M. D., & Cunningham, P. B. (1998). Multisystemic Treatment of Antisocial Behavior in Children and Adolescents. New York: Guilford.Google Scholar
  27. Higgins, S. T., Budney, A. J., & Bickel, W. K. (1994). Applying behavioral concepts and principles to the treatment of cocaine dependence. Drug and Alcohol Dependence, 34, 87–97.PubMedCrossRefGoogle Scholar
  28. Higgins, S. T., & Silverman, K. (Eds.) (1999). Motivating Behavior Change Among Illicit-Drug Abusers. Washington, DC: American Psychological Association.Google Scholar
  29. Hurt, R. D., Croghan, G. A., Beede, S. D., Wolter, T. D., Croghan, I. T., & Patten, C. A. (2000). Nicotine patch therapy in 101 adolescent smokers: Efficacy, withdrawal symptoms relief, and carbon monoxide and plasma cotinine levels. Archives of Pediatric and Adolescent Medicine, 154, 31–37.Google Scholar
  30. Joanning, H., Quinn, Q., Thomas, F., & Mullen, R. (1992). Treating adolescent drug abuse: A comparison of family systems therapy, group therapy, and family drug education. Journal of Marital and Family Therapy, 18, 345–356.CrossRefGoogle Scholar
  31. Johnston, L. D., O’Malley, P. M., Bachman, J. G., & Schulenberg, J. E., (2004). Monitoring the Future National Results on Adolescent Drug Use: Overview of Key Findings, 2003 (NIH Publication No. 04-5506). Bethesda, MD: National Institute on Drug Abuse.Google Scholar
  32. Kaminer, Y., Buckstein, O. G., & Tarter, R. E. (1991). The teen addiction severity index: Rationale and reliability. International Journal of Addiction, 26, 219–226.Google Scholar
  33. Kaminer, Y., Burleson, J., Blitz, C., Sussman, J., & Rounsaville, B. J. (1998). Psychotherapies for adolescent substance abusers: A pilot study. The Journal of Nervous and Mental Disease, 186, 684–690.PubMedCrossRefGoogle Scholar
  34. Kaminer, Y., Burleson, J., & Goldberger, R. (2002). Psychotherapies for adolescent substance abusers: Short- and long-term outcomes. Journal of Nervous and Mental Disease, 190, 737–745.PubMedCrossRefGoogle Scholar
  35. Kaminer, Y., & Slesnick, N. (2005). Evidence-based cognitive-behavioral and family therapies for adolescent alcohol and other substance use disorders. Recent Developments in Alcoholism, 17, 383–405.PubMedCrossRefGoogle Scholar
  36. Kamon, J., Budney, A., & Stanger, C. (2005). A contingency management intervention for adolescent marijuana abuse and conduct problems. Journal of the American Academy of Child and Adolescent Psychiatry, 6(6), 513–521.CrossRefGoogle Scholar
  37. Killen, J. D., Robinson, T. N., Ammerman, S., Hayward, C., Rogers, J., & Stone, C. (2004). Randomized clinical trial of the efficacy of bupropion combined with the nicotine patch in the treatment of adolescent smokers. Journal of Consulting and Clinical Psychology, 72, 729–735.PubMedCrossRefGoogle Scholar
  38. Kikpatrick, D. G., Acierno, R., Saunders, B., Resnick, H. S., Best, C. L., & Schnurr, P. P. (2000). Risk factors for adolescent substance abuse and dependence: Data from a national sample. Journal of Consulting and Clinical Psychology, 1(1), 19–30.CrossRefGoogle Scholar
  39. Latimer, W. W., Winters, K. C., D’Zurilla, T., & Nichols, M. (2003). Integrated family and cognitive-behavioral therapy for adolescent substance abusers: A stage I efficacy study. Drug and Alcohol Dependence, 71, 303–317.PubMedCrossRefGoogle Scholar
  40. Lewis, R. A., Piercy, F. P., Sprenkle, D. H., & Trepper T. S. (1990). Family-based interventions for helping drug-abusing adolescents. Journal of Adolescent Research, 5, 82–95.CrossRefGoogle Scholar
  41. Liddle, H. A. (2002). Multidimensional Family Therapy for Adolescent Cannabis Users, Cannabis Youth Treatment Series, Vol. 5 (DHHS Publication no. 02-3660). Rockville, MD: Center for Substance Abuse Treatment, Substance Abuse and Mental Health Services Administration. Retrieved December 9, 2006, from http://www. kap. samhsa. gov/products/manuals/cyt/pdfs/cyt5.pdf.Google Scholar
  42. Liddle, H. A. (2004). Family-based therapies for adolescent alcohol and drug use: Research contributions and future research needs. Addiction, 99(S2), 76–92.PubMedCrossRefGoogle Scholar
  43. Liddle, H. A., Dakof, G. A., Parker, K., Diamond, G. S., Barrett, K., & Tejeda, M. (2001). Mulitdimensional family therapy for adolescent drug use: Results of a randomized clinical trial. American Journal of Drug and Alcohol Abuse, 4(4), 651–688.CrossRefGoogle Scholar
  44. Liddle, H. A., Rowe, C. L., Dakof, G. A., Ungaro, R. A., & Henderson, C. E. (2004). Early intervention for adolescent substance abuse: Pretreatment to posttreatment outcomes of a randomized clinical trial comparing multidimensional family therapy to peer group treatment. Journal of Psychoactive Drugs, 36(1), 49–63.PubMedGoogle Scholar
  45. Littell, J. H., Popa, M., & Forsythe, B. (2005). Multisystemic therapy for social, emotional, and behavioral problems in youth aged 10–17. Cochrane Database Systems Review, 20(3).Google Scholar
  46. Marlatt, G. A., Baer, J. S., Kivlahan, D. R., Dimeff, L. A., Larimer, M. E., Quigley, L. A., et al. (1998). Screening and brief intervention for high-risk college student drinkers: Results from a 2-year follow-up assessment. Journal of Consulting and Clinical Psychology, 66, 604–615.PubMedCrossRefGoogle Scholar
  47. Marsch, L. A., Bickel, W. K., Badger, G. J., Stcothart, M. E., Quesnal, K. J., Stanger, C., et al. (2005). Comparison of pharmacological treatments for opioid-dependent adolescents. Archives of General Psychiatry, 62, 1157–1164.PubMedCrossRefGoogle Scholar
  48. Mayhew, D. R., Donelson, A. C., Beirness, D. J., & Simpson, H. M. (1989). Youth alcohol and relative risk of crash involvement. Accident; Analysis and Prevention, 4(4), 273–287.Google Scholar
  49. McCambridge, J., & Strang, J. (2004). The efficacy of single-session motivational interviewing in reducing drug consumption and perceptions of drug-related risk and harm among young people: Results from a multi-site cluster randomized trial. Addiction , 99(S2), 63–75.CrossRefGoogle Scholar
  50. McLaughlin, C. R., Daniel, J., & Joost, T. F. (2000). The relationship between substance use, drug selling, and lethal violence in 25 juvenile murderers. Journal of Forensic Sciences, 45, 349–353.PubMedGoogle Scholar
  51. Miller, W. R., & Rollnick, S. (2002). Motivational Interviewing: Preparing People for Change, 2nd ed. New York: Guilford Press.Google Scholar
  52. Monti, P. M., Barnett, N. P., O’Leary, T. A., & Colby, S. M. (2001a). Motivational enhancement for alcohol-involved adolescents. In P. M. Monti, S. M. Colby, & T. A. O’Leary (Eds.), Adolescents, Alcohol, and Substance Abuse: Reaching Teens Through Brief Interventions (pp. 145–182). New York: Guilford Press.Google Scholar
  53. Monti, P. M., Colby, S. M., Barnett, N. P., Spirito, A., Rohsenow, D. J., Myers, M., et al. (1999). Brief intervention for harm reduction with alcohol-positive older adolescents in a hospital emergency department. Journal of Consulting and Clinical Psychology, 67, 989–994.PubMedCrossRefGoogle Scholar
  54. Monti, P. M., Colby, S. M., & O’Leary, T. A. (2001b). Adolescents, Alcohol, and Substance Abuse: Reaching Teens Through Brief Interventions. New York: Guilford Press.Google Scholar
  55. Moolchan, E. T., Robinson, M. L., Ernst, M., Cadet, J. L., Pickworth, W. B., Heishman, S. J., et al. (2004). Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addiction. Pediatrics, 115, 407–414.CrossRefGoogle Scholar
  56. O’Leary, T. T., & Monti, P. M. (2004). Motivational enhancement and other brief interventions for adolescent substance abuse: Foundations, applications, and evaluations. Addiction, 99(S2), 63–75.CrossRefGoogle Scholar
  57. Ozechowski, T. J., & Liddle, H. A. (2000). Family-based therapy for adolescent drug abuse: Knowns and unknowns. Clinical Child and Family Psychology Review, 3 (4), 269–298.PubMedCrossRefGoogle Scholar
  58. Randall, J., & Cunningham, P. B. (2003). Multisystemic therapy: A treatment for violentsubstance-abusing and substance-dependent juvenile offenders. Addictive Behaviors, 28 (9), 1731–1739.PubMedCrossRefGoogle Scholar
  59. Randall, J., Henggeler, S. W., Cunningham, P. B., Rowland, M. D., & Swenson, C. C. (2001). Adapting multisystemic therapy to treat adolescents substance abuse more effectively. Cognitive and Behavioral Practice, 8 (4), 359–366.CrossRefGoogle Scholar
  60. Robbins, M. S., Bachrach, K., & Szapocznik, J. (2002). Bridging the research-practice gap in adolescent substance abuse treatment: The case of brief strategic family therapy. Journal of Substance Abuse Treatment, 23 (2), 123–132.PubMedCrossRefGoogle Scholar
  61. Sampl, S., & Kadden, R. (2001). Motivational Enhancement Therapy and Cognitive Behavioral Therapy for Adolescent Cannabis Users: 5 Sessions, Cannabis Youth Treatment Series, Vol. 1 (DHHS Publication No. 01-3486). Rockville, MD: Center for Substance Abuse Treatment, Substance Abuse and Mental Health Services Administration. Retrieved December 9, 2006, from http://www.kap. samhsa. gov/products/manuals/cyt/pdfs/cyt1. pdf.Google Scholar
  62. Santisteban, D. A., Coatsworth, J. D., Perez-Vidal, A., Kurtines, W. M., Schwartz, S. J., LaPerrier, A., et al. (2003). Efficacy of brief strategic family therapy in modifying hispanic adolescent behavior problems and substance use. Journal of Family Psychology, 1(1), 121–133.CrossRefGoogle Scholar
  63. Schottenfeld, R. S. (2004). Opioids: Maintenance treatment. In M. Galanter & H. D. Kleber (Eds.), Textbook of Substance Abuse Treatment (pp. 291–304). Washington, DC: American Psychiatric Publishing.Google Scholar
  64. Smith, T. A., House, R. F., Croghan, I. T., Gauvin, T. R., Colligan, R. C., Offord, K. P., et al. (1996). Nicotine patch therapy in adolescent smokers. Pediatrics, 98, 659–667.PubMedGoogle Scholar
  65. Swadi, H. (1999). Individual risk factors for adolescent substance use. Drug and Alcohol Dependence, 55, 209–224.PubMedCrossRefGoogle Scholar
  66. Szapocznik, J., Hervis, O., & Schwartz, S. (2003). Brief Strategic Family Therapy for Adolescent Drug Abuse. Therapy Manuals for Drug Addiction (NIH Publication No. 03-4751). Retrieved December 9, 2006, from Scholar
  67. Upadhyaya, H. P., Deas, D., & Brady, K. T. (2005). A practical clinical approach to the treatment of nicotine dependence in adolescents. Journal of American Academy of Child and Adolescent Psychiatry, 44, 942–946.CrossRefGoogle Scholar
  68. Vandrey, R., Budney, A. J., Kamon, J. L., & Stanger, C. (2005). Cannabis withdrawal in adolescent treatment seekers. Drug and Alcohol Dependence, 78, 205–210.PubMedCrossRefGoogle Scholar
  69. Waldron, H. B., Slesnick, N., Brody, J. L., Turner, C. W., & Peterson, T. R. (2001). Treatment outcomes for adolescent substance abuse at 4- and 7-month assessments. Journal of Consulting and Clinical Psychology, 5(5), 802–813.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Deborah Deas
  • Kevin Gray
  • Himanshu Upadhyaya

There are no affiliations available

Personalised recommendations