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Synthesis and Biological Activity of Novel α-Conotoxin Analogues Incorporating Substituted Proline Derivatives

  • Christopher J. Armishaw
  • Anders A. Jensen
  • Christian Skonberg
  • Tommy Liljefors
  • Kristian Strømgaard
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Ligand Binding Pocket Side Chain Ring Neuronal Nicotinic Acetylcholine Receptor Share Sequence Homology Recent Crystal Structure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

CJA is funded by a Drug Research Academy post-doctoral fellowship.

References

  1. 1.
    Armishaw, C. J. and Alewood, P. F., Curr. Protein Pept. Science, 6, 221–240 (2005).CrossRefGoogle Scholar
  2. 2.
    Celie, P. H. N., et al., Nature Struc. Mol. Biol., 12, 582–588 (2005).CrossRefGoogle Scholar
  3. 3.
    Hansen, S. B., et al., EMBO J., 24, 3635–3646 (2005).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Christopher J. Armishaw
    • 1
  • Anders A. Jensen
    • 1
  • Christian Skonberg
    • 2
  • Tommy Liljefors
    • 1
  • Kristian Strømgaard
    • 1
  1. 1.Department Medicinal Chemistry and ChemistryFaculty of Pharmaceutical Sciences, University of CopenhagenCopenhagen ØDenmark
  2. 2.Department of Pharmaceutics and Analytical ChemistryFaculty of Pharmaceutical Sciences, University of CopenhagenCopenhagen ØDenmark

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