Development of an Efficient Solid-Phase Synthetic Methodology to Construct a Combinatorial Library of a Potent HDAC Inhibitor

  • Salvatore Di Maro
  • Jung-Mo Ahn
Part of the Advances in Experimental Medicine and Biology book series (volume 611)


HDAC Inhibitor Hydroxamic Acid Cyclic Peptide Sodium Butyrate Reductive Amination 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The work was supported by University of Texas at Dallas and Welch Foundation (J.-M.A. AT-1595); and University of Naples “Federico II” (S.D.M).


  1. 1.
    Hassig, C. A. and Schreiber, S. L. Curr. Opin. Chem. Biol. 1, 300–308 (1997).CrossRefGoogle Scholar
  2. 2.
    Monneret, C. Eur. J. Med. Chem. 40, 1–13 (2005).CrossRefGoogle Scholar
  3. 3.
    Furumai, R., et al. Cancer Res. 62, 4916–4921 (2002).Google Scholar
  4. 4.
    Li, K. W., et al. J. Am. Chem. Soc. 118, 7237–7238 (1996).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Salvatore Di Maro
    • 1
    • 2
  • Jung-Mo Ahn
    • 1
  1. 1.Department of ChemistryUniversity of Texas at DallasRichardsonUSA
  2. 2.Department of Pharmacological and Toxicological ChemistryUniversity of Naples “Federico II”NaplesItaly

Personalised recommendations