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Racemization-free segment condensation based on the O-acyl isopeptide method: Toward a chemical protein synthesis on solid support

  • Taku Yoshiya
  • Youhei Sohma
  • Yoshio Hamada
  • Tooru Kimura
  • Yoshio Hayashi
  • Yoshiaki Kiso
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

HPLC Analysis Condensation Reaction Solid Support Synthetic Method Model Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This research was supported in part by The “Academic Frontier” Project for Private Universities: matching fund subsidy from MEXT (Ministry of Education, Culture, Sports, Science and Technology) of the Japanese Government, and The 21st Century COE Program from MEXT.

References

  1. 1.
    Yoshiya, T., Sohma, Y., Kimura, T., Hayashi, Y. and Kiso, Y. Tetrahedron Lett. 47, 7905– 7909 (2006).CrossRefGoogle Scholar
  2. 2.
    Yoshiya, T., Taniguchi, A., Sohma, Y., Fukao, F., Nakamura, S., Abe, N., Ito, N., Skwarczynski, M., Kimura, T., Hayashi, Y. and Kiso, Y. Org. Biomol. Chem. 5, 1720– 1730 (2007).CrossRefGoogle Scholar
  3. 3.
    Sohma, Y., Yoshiya, T., Taniguchi, A., Kimura, T., Hayashi, Y. and Kiso, Y. Biopolymers (Pept. Sci.) 88, 253–262 (2007)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Taku Yoshiya
    • 1
  • Youhei Sohma
    • 1
  • Yoshio Hamada
    • 1
  • Tooru Kimura
    • 1
  • Yoshio Hayashi
    • 1
  • Yoshiaki Kiso
    • 1
  1. 1.Department of Medicinal Chemistry, Center for Frontier Research in Medicinal Science, 21st Century COE ProgramKyoto Pharmaceutical UniversityJapan

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