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Development of a small molecule peptidomimetic affinity Ligand for efficient purification of the large protein Factor VIII

  • Sebastian Knör
  • Burkhardt Laufer
  • Alexey Khrenov
  • Abdellah Benhida
  • Sabrina C. Grailly
  • Nathalie Beaufort
  • Viktor Magdolen
  • Charlotte A. E. Hauser
  • Evgueni L. Saenko
  • Jean-Marie R. Saint-Remy
  • Horst Kessler
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Factor VIII Preparative Scale Immunoaffinity Chromatography Reductive Alkylation Amine Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Jacquemin, M., De Maeyer, M., D'Oiron, R., Lavend'Homme, R., Peerlinck, K. and Saint-Remy, J.-M. J. Thromb. Haemost. 1, 456–463 (2003).CrossRefGoogle Scholar
  2. 2.
    Ananyeva, N., Khrenov, A., Darr, F., Summers, R., Sarafanov, A. and Saenko, E. Expert. Opin. Pharmacother. 5, 1061–1070 (2004).CrossRefGoogle Scholar
  3. 3.
    Pflegerl, K., Hahn, R., Berger, E. and Jungbauer, A. J. Pept. Res. 59, 174–182 (2002).CrossRefGoogle Scholar
  4. 4.
    Knör, S., Khrenov, A. V., Laufer, B., Saenko, E. L., Hauser, C. A. E. and Kessler, H. J. Med. Chem. 50, 4329–4339 (2007).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Sebastian Knör
    • 1
  • Burkhardt Laufer
    • 1
  • Alexey Khrenov
    • 2
  • Abdellah Benhida
    • 3
  • Sabrina C. Grailly
    • 3
  • Nathalie Beaufort
    • 4
  • Viktor Magdolen
    • 4
  • Charlotte A. E. Hauser
    • 5
  • Evgueni L. Saenko
    • 2
  • Jean-Marie R. Saint-Remy
    • 3
  • Horst Kessler
    • 1
  1. 1.Department ChemieTU MünchenGarchingGermany
  2. 2.School of MedicineUniversity of MarylandBaltimoreUSA
  3. 3.Center for Molecular & Vascular BiologyKU LeuvenLeuvenBelgium
  4. 4.Klinische Forschergruppe der TU MünchenMünchenGermany
  5. 5.Klinik für Frauenheilkunde & Geburtshilfe der Universität zu LübeckLübeckGermany

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