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A Novel Method for the Preparation of Peptide Thioester and its Application to Glycoprotein Synthesis

  • Hironobu Hojo
  • Yuko Onuma
  • Yuri Akimoto
  • Yuko Nakahara
  • Yoshiaki Nakahara
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Acyl Transfer 433A Peptide Crude Peptide Glycoprotein Synthesis Native Chemical Ligation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

We thank Mr. Hiroaki Asai of Otsuka Chemical Company for providing Fmoc-Asn carrying nonasaccharide. We also thank Prof. Yasuhiro Kajihara of Yokohama City University for helpful discussions about the introduction of Fmoc-Asn carrying unmasked carbohydrate.

References

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    Kajihara, Y., Yoshihara, A., Hirano, K. and Yamamoto, N. Carbohydr. Res. 341, 1333– 1340 (2006).CrossRefGoogle Scholar
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    Hojo, H., Haginoya, E., Matsumoto, Y., Nakahara, Y., Nabeshima, K., Toole, B. P. and Watanabe, Y. Tetrahedron Lett., 44, 2961–2964 (2003).CrossRefGoogle Scholar
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    Aimoto, S. Biopolymers (Pept. Sci.) 51, 247–265 (1999).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Hironobu Hojo
    • 1
  • Yuko Onuma
    • 1
  • Yuri Akimoto
    • 1
  • Yuko Nakahara
    • 1
  • Yoshiaki Nakahara
    • 1
  1. 1.Department of Applied BiochemistryInstitute of Glycotechnology, Tokai UniversityHiratsukaJapan

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