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Facile Synthesis of Glucagon-Like Peptide-1 (GLP-1) Mimetics

  • Sun-Young Han
  • Martin Beinborn
  • Jung-Mo Ahn
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Facile Synthesis Amidation Reaction Stimulate cAMP Production Inhibit Glucagon Secretion Control Glucose Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The work was supported by Welch Foundation (AT-1595), American Diabetes Association (7-07-JF-02), and Texas Advanced Research Program (009741-0031-2006).ter>

References

  1. 1.
    Horwell, D. C., et al. Bioorg. Med. Chem. 4, 33–42 (1996).CrossRefGoogle Scholar
  2. 2.
    Jacoby, E. Bioorg. Med. Chem. Lett. 12, 891–893 (2002).CrossRefGoogle Scholar
  3. 3.
    Orner, B. P., et al. J. Am. Chem. Soc. 123, 5382–5383 (2001).CrossRefGoogle Scholar
  4. 4.
    Ernst, J. T., et al. Angew. Chem. Int. Ed. 42, 535–539 (2003).CrossRefGoogle Scholar
  5. 5.
    Oguri, H., et al. Tetrahedron Lett. 46, 21797#x2013;2183 (2005).CrossRefGoogle Scholar
  6. 6.
    Drucker, D. J. Diabetes Care 26, 2929–2940 (2003).CrossRefGoogle Scholar
  7. 7.
    Thornton, K. and Gorenstein, D. G. Biochemistry 33, 3532–3539 (1994).CrossRefGoogle Scholar
  8. 8.
    Knudsen, L. B., et al. Proc. Natl. Acad. Sci. USA 104, 937–942 (2007).CrossRefGoogle Scholar
  9. 9.
    Chen, D., et al. Proc. Natl. Acad. Sci. USA 104, 9437#x2013;948 (2007).Google Scholar
  10. 10.
    Ahn, J.-M. and Han, S.-Y. Tetrahedron Lett. 48, 3543–3547 (2007).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Sun-Young Han
    • 1
  • Martin Beinborn
    • 2
  • Jung-Mo Ahn
    • 1
  1. 1.Department of ChemistryUniversity of Texas at DallasRichardsonUSA
  2. 2.Department of Medicine and Molecular Pharmacology Research CenterTupper Research Institute, New England Medical CenterBostonUSA

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