Advertisement

Novel Bifunctional Peptides as Opioid Agonists and NK-1 Antagonists

  • Padma Nair
  • Takashi Yamamoto
  • Vinod Kulkarni
  • Sharif Moye
  • Edita Navratilova
  • Peg Davis
  • Tally Largent
  • Shou-wu Ma
  • Henry I. Yamamura
  • Todd Vanderah
  • Josephine Lai
  • Frank Porreca
  • Victor J. Hruby
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Opioid Receptor Opioid Agonist Benzyl Ester Protect Amino Acid Analgesic Tolerance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The work was funded by U. S Public Health Service, National Institute of Drug Abuse.

References

  1. 1.
    Khasabov, S.G., Rogers, S.D., Ghilardi, J.R., Peters, C.M., Mantyh, P.W., Simone, D.A., J. Neurosci. 22, 9086–98 (2002).Google Scholar
  2. 2.
    Powell, K.J., Quirion, R., Jhamandas, K. Neuroscience, 18, 1572–83 (2003).Google Scholar
  3. 3.
    Yamamoto, T., Nair, P., Davis, P., Ma, S.W., Moye, M., Largent-Milnes, T., Vanderah, T.W., Lai, J., Porreca, F.; Yamamura, H.I., Hruby, V.J. J. Med Chem., 50, 2779–86 (2007).CrossRefGoogle Scholar
  4. 4.
    Bonney, I.M., Foran, S.E., Marchand, J.E., Lipkowski, A.W., Carr, D.B. Eur. J. Pharmacol., 488, 91–99 (2004).CrossRefGoogle Scholar
  5. 5.
    Horan, P. J., Mattia, A., Bilsky, E.J., Weber, S., Davis, T.P., Yamamura, H.I., Malatynska, E., Appleyard, S.M., Slaninova, J., Misicka, A., Lipowski, A.W., Hruby, V.J., Porreca, F. J. Pharmacol Exp. Ther. 265, 1446–54 (1993).Google Scholar
  6. 6.
    Macleod, A.M., Merchant, K.J., Cascieri, M.A., Sadowski, S., Ber, E., Swain, C.J., Baker, R. J. Med Chem., 14, 2044–5 (1993).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Padma Nair
    • 1
  • Takashi Yamamoto
    • 1
  • Vinod Kulkarni
    • 1
  • Sharif Moye
    • 2
  • Edita Navratilova
    • 2
  • Peg Davis
    • 2
  • Tally Largent
    • 2
  • Shou-wu Ma
    • 2
  • Henry I. Yamamura
    • 2
  • Todd Vanderah
    • 2
  • Josephine Lai
    • 2
  • Frank Porreca
    • 2
  • Victor J. Hruby
    • 1
  1. 1.Departments of ChemistryUniversity of ArizonaTucsonU.S.A.
  2. 2.PharmacologyUniversity of ArizonaTucsonU.S.A.

Personalised recommendations