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Synthesis of Bivalent MSH Ligands and Evaluation of their Binding to hMC4R using MSH Lanthaligand

  • Steve M. Fernandes
  • Rajesh Sankaranarayanan
  • Liping Xu
  • Jatinder Josan
  • Josef Vagner
  • Robert Gillies
  • Victor J. Hruby
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Acetic Anhydride Carbonyl Diimidazole Competition Binding Assay Bivalent Ligand Peptide Chain Elongation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The work was funded by grants from USPHS, NCI and the AZ Biological Research Commission.

References

  1. 1.
    Sankaranarayanan, R., Hruby, V.J., et al. Bioconjugate Chemistry, 18(4), 1101–1119 (2007).CrossRefGoogle Scholar
  2. 2.
    Handl, H.L., Hruby, V.J., Gillies, R.J., et al. Analytical Biochemistry 343, 299–307 (2005).CrossRefGoogle Scholar
  3. 3.
    Albericio, F., Thieriet, N., et al. Tetrahedron Letters 38(41), 7275–7278 (1997).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Steve M. Fernandes
    • 1
  • Rajesh Sankaranarayanan
    • 2
  • Liping Xu
    • 1
  • Jatinder Josan
    • 2
  • Josef Vagner
    • 2
  • Robert Gillies
    • 1
  • Victor J. Hruby
    • 1
    • 2
  1. 1.Department of Biochemistry and Molecular BiophysicsUniversity of ArizonaTucsonUSA
  2. 2.Department of ChemistryUniversity of ArizonaTucsonUSA

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