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Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors — A Step Towards Personal Medicine

  • Jatinder S. Josan
  • Rajesh Sankaranarayanan
  • Heather L. Hand
  • Steve Fernandes
  • Liping Xu
  • Josef Vagner
  • Robert J. Gillies
  • Victor J. Hruby
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Hek293 Cell Line Tissue Expression Profile Differentiate Cancer Cell Rink Amide Resin Current Cancer Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The work was supported by NIH R33 CA95944, R01 CA97360 and the Arizona Biomedical Research Commission.

References

  1. 1.
    Caplan M. R., Rosca E. V. Ann. Biomed. Eng. 33, 1113–1124 (2005).CrossRefGoogle Scholar
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    Gillies R. J., Hruby V. J. Expert Opin. Ther. Targets. 7, 137–139 (2003).CrossRefGoogle Scholar
  3. 3.
    Vagner J., Handl H. L., Gillies R. J., Hruby V. J. Bioorg. Med. Chem. Lett. 2004, 211–215 (2004).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Jatinder S. Josan
    • 1
  • Rajesh Sankaranarayanan
    • 1
  • Heather L. Hand
    • 3
  • Steve Fernandes
    • 1
  • Liping Xu
    • 4
  • Josef Vagner
    • 1
    • 4
  • Robert J. Gillies
    • 2
    • 3
    • 4
  • Victor J. Hruby
    • 1
    • 3
    • 4
  1. 1.Departments of ChemistryUniversity of ArizonaTucsonUSA
  2. 2.RadiologyUniversity of ArizonaTucsonUSA
  3. 3.Biochemistry & Molecular BiophysicsUniversity of ArizonaTucsonUSA
  4. 4.BIO5 InstituteUniversity of ArizonaTucsonUSA

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