A combination of ligand SAR and receptor site-directed mutagenesis reveals requirements for antagonist activity at the melanocortin-3 receptor

  • Bettina Proneth
  • Federico P. Portillo
  • Carrie Haskell-Luevano
Part of the Advances in Experimental Medicine and Biology book series (volume 611)


Para Position Antagonist Activity Melanocortin Receptor Potent Antagonist Rational Drug Design 
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The work was funded by the NIH RO1DK57080 grant.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Bettina Proneth
    • 1
  • Federico P. Portillo
    • 1
  • Carrie Haskell-Luevano
    • 1
  1. 1.Department of Medicinal ChemistryUniversity of FloridaGainesvilleUSA

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