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Tailor made Pharmacokinetics of Peptides by Transient PEGylation

  • Ulrich Hersel
  • Martina Kreuzer
  • Harald Rau
  • Dirk Vetter
  • Thomas Wegge
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Half Life Time Ester Prodrug Unmodified Peptide Plasma Glucose Lowering Intrapatient Variability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Greenwald R. B., Yang K., Zhao H., et al. Bioconjugate Chem. 14, 395–403 (2003). Greenwald R. B., Choe Y. H., Conover C. D., et al. J. Med. Chem. 43, 475–487 (2000). Tsubery H., Mironchik M., Fridkin M., et al. J. Biol. Chem. 279, 38118–38124 (2004).CrossRefGoogle Scholar
  2. 2.
    Hersel U., Rau H., Schnepf R., et al. WO2005099768.Google Scholar
  3. 3.
    Wegge T., Fricker G., Hersel U., et al. 8th German Peptide Symposium, P026 (2007).Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Ulrich Hersel
    • 1
  • Martina Kreuzer
    • 1
  • Harald Rau
    • 1
  • Dirk Vetter
    • 1
  • Thomas Wegge
    • 1
  1. 1.Complex Biosystems GmbHHeidelbergGermany

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