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pH Controlled Aggregation Morphology of Aβ(16–22): Formation of Peptide Nanotubes, Helical Tapes and Amyloid Fibrils

  • Ronald C. Elgersma
  • Dirk T. S. Rijkers
  • Rob M. J. Liskamp
Part of the Advances in Experimental Medicine and Biology book series (volume 611)

Keywords

Amyloid Fibril Supramolecular Assembly Amyloid Formation Gelation Behavior Helical Ribbon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

These investigations were supported by the council for Chemical Sciences of the Netherlands-Organization for Scientific Research (CW-NWO).

References

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    Elgersma, R. C.; Meijneke, T.; Posthuma, G.; Rijkers, D. T. S.; Liskamp, R. M. J. Chem. Eur. J. 12, 3714–3725 (2006).CrossRefGoogle Scholar
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    Elgersma, R. C.; Meijneke, T.; de Jong, R.; Brouwer, A. J.; Posthuma, G.; Rijkers, D. T. S.; Liskamp, R. M. J. Org. Biomol. Chem. 4, 3587–3597 (2006).CrossRefGoogle Scholar
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    Lu, K.; Jacob, J.; Thiyagarajan, P.; Conticello, V. P.; Lynn, D. G. J. Am. Chem. Soc. 125, 6391–6393 (2003).CrossRefGoogle Scholar
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    Reches, M.; Gazit, E. Science 300, 625–627 (2003).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Ronald C. Elgersma
    • 1
  • Dirk T. S. Rijkers
    • 1
  • Rob M. J. Liskamp
    • 1
  1. 1.Medicinal Chemistry & Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Faculty of ScienceUtrecht UniversityUtrechtThe Netherlands

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