Phe-Aib Hydroxyethylene Dipeptide Isostere Synthesis

  • Nicolas Genest
  • Susan Del Valle
  • Teresa Lama
  • Willam D. Lubell
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (volume 611)


Acetic Anhydride Oxidative Cleavage Sodium Chlorite Amine Salt Magnesium Bromide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The work was funded by the GRUM and NSERC.


  1. 1.
    Leung, D., Abbenante, G. and Fairlie, D. P. J. Med. Chem. 43, 305–341 (2000).CrossRefGoogle Scholar
  2. 2.
    Ghosh, A. K. et al. J. Med. Chem. 49, 5252–5261 (2006).CrossRefGoogle Scholar
  3. 4.
    Banerjee, A., Drew, M. G. B. and Haldar, D. Tetrahedron 63, 5561–5566 (2007).CrossRefGoogle Scholar
  4. 4.
    Lama, T., Del Valle, S. E., Genest, N. and Lubell, W. D. Int. J. Pept. Res. Ther. 13, 355– 366 (2007).CrossRefGoogle Scholar
  5. 5.
    Hansford, K. A., Dettwiler, J. E. and Lubell, W. D. Org. Lett. 5, 4887–4890 (2003).CrossRefGoogle Scholar
  6. 6.
    O'Donnell, M. J. and Polt, R. L. J. Org. Chem. 47, 2663–2666 (1982).CrossRefGoogle Scholar
  7. 7.
    Cervantes-Lee, F., Maslouh, N. and Hoffman, R. V. J. Org. Chem. 67, 1045–1056 (2002).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Nicolas Genest
    • 2
  • Susan Del Valle
    • 1
  • Teresa Lama
    • 2
  • Willam D. Lubell
    • 2
  1. 1.Department of ChemistryNew Mexico State UniversityLas CrucesNew Mexico
  2. 2.Departement de ChimieUniversité de MontréalMontréalCanada

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