Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease

  • Shervin Rabizadeh
  • Maria Oliva-Hemker


Inflammatory Bowel Disease Ulcerative Colitis Primary Sclerosing Cholangitis Inflammatory Bowel Disease Patient Crohn Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Levine JB, Lukawski-Trubish D. Extraintestinal considerations in inflammatory bowel disease. Gastroenterol Clin North Am 1995;24:633.PubMedGoogle Scholar
  2. 2.
    Bhagat S, Das KM. A shared and unique peptide in the human colon, eye, and joint detected by a monoclonal antibody. Gastroenterology 1994;107:103.PubMedGoogle Scholar
  3. 3.
    Rothfuss KS, Stange EF, Herrlinger KR. Extraintestinal manifestations and complications in inflammatory bowel disease. World J Gastroenterol 2006;12:4819.PubMedGoogle Scholar
  4. 4.
    Adams DH, Eksteen B. Aberrant homing of mucosal T cells and extra-intestinal manifestations of inflammatory bowel disease. Nat Rev Immunol 2006;6:244.PubMedCrossRefGoogle Scholar
  5. 5.
    Danese S, Semeraro S, Papa A, Roberto I, Scaldaferri F, Fedeli G, Gasbarrini G, Gasbarrini A. Extraintestinal manifestations in inflammatory bowel disease. World J Gastroenterol 2005;11:7227.PubMedGoogle Scholar
  6. 6.
    Oliva-Hemker M. More than a gut reaction: Extraintestinal complications of IBD. Contemporary Pediatrics 1999;16:45.Google Scholar
  7. 7.
    Lichtman SN, Sartor RB: Extraintestinal manifestations of inflammatory bowel disease: clinical aspects and natural history. In Targan S and Shanahan F (eds): Inflammatory Bowel Disease: From Bench to Bedside, Baltimore, MD, Williams and Wilkins, 1994.Google Scholar
  8. 8.
    Hyams JS. Extraintestinal manifestations of inflammatory bowel disease in children. J Pediatr Gastroenterol Nutr 1994;19:7.PubMedCrossRefGoogle Scholar
  9. 9.
    Kethu SR. Extraintestinal manifestations of inflammatory bowel disease. J of Clinical Gastroenterology 2006;40: 467.CrossRefGoogle Scholar
  10. 10.
    Urlep D, Mamula P, Baldassano R. Extraintestinal manifestations of inflammatory bowel disease. Minerva Gastroenterologica e Dietologica 2005;51:147.PubMedGoogle Scholar
  11. 11.
    Loftus EV. Management of extraintestinal manifestations and other complications of inflammatory bowel disease. Current Gastroenterology Reports 2004;6:506.PubMedCrossRefGoogle Scholar
  12. 12.
    Hoffmann RM, Kruis W. Rare extraintestinal manifestations of inflammatory bowel disease. Inflammatory Bowel Diseases 2004;10:140.PubMedCrossRefGoogle Scholar
  13. 13.
    Su CG, Judge TA, Lichtenstein GR. Extraintestinal manifestations of inflammatory bowel disease. Gastroenterology Clinics of North America 2002;31:307.PubMedCrossRefGoogle Scholar
  14. 14.
    Kanof ME, Lake AM, Bayles TM. Decreased height velocity in children and adolescents before the diagnosis of Crohn disease. Gastroenterology 1988;95:1523.PubMedGoogle Scholar
  15. 15.
    Oliva MM, Lake AM. Nutritional considerations and management of the child with inflammatory bowel disease. Nutrition 1996;12:151.PubMedCrossRefGoogle Scholar
  16. 16.
    Passo MH, Fitzgerald JF, Brandt KD. Arthritis associated with inflammatory bowel disease in children—relationship of joint disease to activity and severity of bowel lesion. Dig Dis Sci 1986;31:492.PubMedCrossRefGoogle Scholar
  17. 17.
    Juillerat P, Mottet C, Froehlich F, Felley C, Vader J, Burnand B, Gonvers J, Michetti P. Extraintestinal manifestations of Crohn disease. Digestion 2005;71:31–36.PubMedCrossRefGoogle Scholar
  18. 18.
    Bernstein CN. Osteoporosis and other complications of inflammatory bowel disease. Current Opinion in Gastroenterology 2002;18:428.PubMedCrossRefGoogle Scholar
  19. 19.
    Gokhale R, Favus MJ, Karrison T, et al. Bone mineral density assessment in children with inflammatory bowel disease. Gastroenterology 1998;114:902PubMedCrossRefGoogle Scholar
  20. 20.
    Hyams JS, Wyzga N, Kreutzer, et al. Alterations in bone metabolism in children with inflammatory bowel disease: an in vitro study. J Pediatr Gastroenterol Nutr 1997;24:289.Google Scholar
  21. 21.
    Bousvaros A, Marcon M, Treem W, Waters P, Issenman R, Couper R, Burnell R, Rosenberg A, Rabinovish E, Kirschner B. Chronic recurrent multifocal osteomyelitis associated with chronic inflammatory bowel disease in children. Digestive Diseases and Science 1999;44:2500–07.CrossRefGoogle Scholar
  22. 22.
    Plauth M, Jenss H, Meyle J. Oral manifestations of Crohn disease. J Clin Gastroenterol 1991;13:29.PubMedCrossRefGoogle Scholar
  23. 23.
    Grilich C, Bogenrieder T, Palitzsch KD, Scholmerich J, Lock G. Orofacial granulomatosis as initial manifestation of Crohn disease: a report of two cases. European Journal of Gastroenterology & Hepatology 2002;13:873–76.CrossRefGoogle Scholar
  24. 24.
    Storwick GS, Prihoda MB, Fulton RJ, et al. Pyodermatitis-pyostomatitis vegetans: a specific marker for inflammatory bowel disease. J Am Acad Dermatol 1994;31:336.PubMedGoogle Scholar
  25. 25.
    Kugathasan S, Miranda A, Nocton J, Drolet BA, Raasch C, Binion DG. Dermatologic manifestations of Crohn disease in children: response to infliximab. J of Pediatr Gastroenterol Nutr 2003;37:150–154.CrossRefGoogle Scholar
  26. 26.
    Hofley P, Roarty J, McGinnity G, et al. Asymptomatic uveitis in children with chronic inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1993;17:397.PubMedGoogle Scholar
  27. 27.
    Feldstein AE, Perrault J, El-Youssif M, et al. Primary sclerosing cholangitis in children: a long-term follow-up study. Hepatology 2003;38:210PubMedCrossRefGoogle Scholar
  28. 28.
    Chalasani N, Baluyut A, Ismail A, et al. Cholangiocarcinoma in patients with primary sclerosing cholangitis: a multicenter case-control study. Hepatology 2000;31:7.PubMedCrossRefGoogle Scholar
  29. 29.
    Margalit M, Elinav H, Ilan Y, Shalit M. Liver abscess in inflammatory bowel disease: report of two cases and review of the literature. J of Gastroenterology and Hepatology 2004;19:1338.CrossRefGoogle Scholar
  30. 30.
    SriRajaskanthan R, Winter M, Muller AF. Venous thrombosis in inflammatory bowel disease. Eur J of Gastroenterology and Hepatology 2005;17:697.CrossRefGoogle Scholar
  31. 31.
    Mader R, Segol O, Adawi M, Trougoboff P, Nussinson E. Arthritis or vasculitis as presenting symptoms of Crohn disease. Rheumatol Int 2005;25:401–05.PubMedCrossRefGoogle Scholar
  32. 32.
    Barthet M, Hastier P, Bernard JP, et al. Chronic pancreatitis and inflammatory bowel disease: true or coincidental association? Am J Gastroenterol 1999;94:2141–8PubMedCrossRefGoogle Scholar
  33. 33.
    Kuzmic AC, Kolacek S, Brkljacic B, Juzjak N. Renal artery stenosis associated with Crohn disease. Pediatr Nephrol 2001;16:371–73.PubMedCrossRefGoogle Scholar
  34. 34.
    Camus P, Piard F, Ashcroft T, et al. The lung in inflammatory bowel disease. Medicine 1993;72:151.PubMedCrossRefGoogle Scholar
  35. 35.
    Al-Binali AM, Scott B, Al-Garni A, Montgomery M, Robertson M. Granulomatous pulmonary disease in a child: an unusual presentation of Crohn disease. Pediatr Pulmonol 2003;36:76–80.PubMedCrossRefGoogle Scholar
  36. 36.
    Haralambou G, Teirstein AS, Gil J, Present D. Bronchiolitis obliterans in a patient with ulcerative colitis receiving mesalamine. Mt Sinai J Med 2001;68:384–88.PubMedGoogle Scholar
  37. 37.
    Lossos A, River Y, Eliakim A, et al. Neurologic aspects of inflammatory bowel disease. Neurology 1995;45:416.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Shervin Rabizadeh
  • Maria Oliva-Hemker
    • 1
  1. 1.Division of Pediatric Gastroenterology and NutritionThe Johns Hopkins University School of MedicineBrady 320, Baltimore

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