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Systemic Diseases and Chronic Rhinosinusitis

  • Christine Reger
  • Christina F. Herrera
  • Megan Abbott
  • Alexander G. Chiu
Chapter

Many systemic diseases can cause nasal symptoms, either as an initial presentation or a manifestation later in the disease process. When patients present with nasal symptoms resembling infection—such as purulent nasal discharge, crusting, and congestion—acute rhinosinusitis is likely to be diagnosed. However, when these symptoms persist despite appropriate medical therapy, other etiologies should be considered. In some cases, underlying inflammation of the nasal mucosa causes recurrent or chronic sinusitis, as in nasal polyposis or allergic rhinitis. Less frequently, systemic rather than local conditions are the cause, requiring a more detailed evaluation, comprehensive systemic management, and long-term follow-up [1]. The number of systemic illnesses that can cause nasal symptoms is substantial; only those most commonly affecting the nose and sinuses are discussed here. For purposes of discussion, the diseases have been categorized as follows: autoimmune disorders, infectious...

Keywords

Human Immunodeficiency Virus Systemic Lupus Erythematosus Cystic Fibrosis Cystic Fibrosis Patient Nasal Mucosa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Christine Reger
  • Christina F. Herrera
  • Megan Abbott
  • Alexander G. Chiu
    • 1
  1. 1.Department of OtorhinolaryngologyUniversity of PennsylvaniaPhiladelphiaUSA

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