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Microarrays pp 169-190 | Cite as

Protein Microarrays for the Detection of Biothreats

  • Amy E. Herr
Part of the Integrated Analytical Systems book series (ANASYS)

Abstract

Although protein microarrays have proven to be an important tool in proteomics research, the technology is emerging as useful for public health and defense applications. Recent progress in the measurement and characterization of biothreat agents is reviewed in this chapter. Details concerning validation of various protein microarray formats, from contact-printed sandwich assays to supported lipid bilayers, are presented. The reviewed technologies have important implications for in vitro characterization of toxin–ligand interactions, serotyping of bacteria, screening of potential biothreat inhibitors, and as core components of biosensors, among others, research and engineering applications.

Keywords

Cholera Toxin Severe Acute Respiratory Syndrome Competition Assay Naval Research Laboratory Protein Microarrays 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Amy E. Herr
    • 1
  1. 1.Department of Bioengineering and Biological SciencesUniversity of California-BerkeleyBerkeley

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