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East Africa – Kenya, Tanzania & Uganda

  • Helen A. Weiss
  • Corinne Merle
  • David Serwadda
  • Saidi H. Kapiga

Keywords

Sexually Transmitted Infection Male Circumcision Genital Ulcer Disease Kagera Region Rakai District 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Adjuik, M., T. Smith, S., Clark, J., Todd, A., Garrib, Y., Kinfu, K., Kahn, M., Mola, A., Ashraf, H., Masanja, K., Adazu, J., Sacarlal, N., Alam, A., Marra, A., Gbangou, Mwageni, E., & Binka, F. (2006). Cause-specific mortality rates in sub-Saharan Africa and Bangladesh. Bulletin of the World Health Organization, 84, 181–8.PubMedCrossRefGoogle Scholar
  2. Ahmed, H.J., Mbwana, J., Gunnarsson, E., Ahlman, K., Guerino, C., Svensson, L.A., Mhalu, F., & Lagergard, T. (2003). Etiology of genital ulcer disease and association with human immunodeficiency virus infection in two Tanzanian cities. Sexually Transmitted Diseases, 30, 114–9.PubMedCrossRefGoogle Scholar
  3. AMREF (2001). Inventory of Agencies with HIV/AIDS Activities and HIV/AIDS Interventions in Uganda 2001. Kampala: Uganda and Uganda AIDS Commission Secretariat.Google Scholar
  4. Ao, T.T., Sam, N.E., Masenga, E.J., Seage, G.R., & Kapiga, S.H. (2006). Human immunodeficiency virus type 1 among bar and hotel workers in northern Tanzania: the role of alcohol, sexual behavior, and herpes simplex virus type 2. Sexually Transmitted Diseases, 33, 163–9.PubMedCrossRefGoogle Scholar
  5. Arroyo, M.A., Sateren, W.B., Serwadda, D., Gray, R.H., Wawer, M.J., Sewankambo, N.K., Kiwanuka, N., Kigozi, G., Wabwire-Mangen, F., Eller, M., Eller, L.A., Birx, D.L., Robb, M.L., & McCutchan, F.E. (2006). Higher HIV-1 incidence and genetic complexity along main roads in Rakai District, Uganda. Journal of Acquired Immune Deficiency Syndrome, 43, 440–5.CrossRefGoogle Scholar
  6. Asiimwe-Okiror, G., Opio, A.A., Musinguzi, J., Madraa, E., Tembo, G., & Carael, M. (1997). Change in sexual behaviour and decline in HIV infection among young pregnant women in urban Uganda. AIDS, 11, 1757–63.PubMedCrossRefGoogle Scholar
  7. Auvert, B., Taljaard, D., Lagarde, E., Sobngwi-Tambekou, J., Sitta, R., & Puren, A. (2005). Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. Public Library of Science Medicine, 2, e298.PubMedGoogle Scholar
  8. Bagasra, O., Kajdacsy-Balla, A., Lischner, H.W., & Pomerantz, R.J. (1993). Alcohol intake increases human immunodeficiency virus type 1 replication in human peripheral blood mononuclear cells. Journal of Infectious Disease, 167, 789–97.Google Scholar
  9. Bailey, R.C., Moses, S., Parker, C.B., Agot, K., Maclean, I., Krieger, J.N., Williams, C.F., Campbell, R.T., & Ndinya-Achola, J.O. (2007). Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet, 369, 643–56.PubMedCrossRefGoogle Scholar
  10. Bakari, M., Lyamuya, E., Mugusi, F., Aris, E., Chale, S., Magao, P., Jossiah, R., Janabi, M., Swai, N., Pallangyo, N., Sandstrom, E., Mhalu, F., Biberfeld, G., & Pallangyo, K. (2000). The prevalence and incidence of HIV-1 infection and syphilis in a cohort of police officers in Dar es Salaam, Tanzania: a potential population for HIV vaccine trials. AIDS, 14, 313–20.PubMedCrossRefGoogle Scholar
  11. Baryarama, F., Bunnell, R., McFarland, W., Hudes, E.S., Neilands, T.B., Ransom, R.L., Mubangizi, J., Hitimana-Lukanika, C., & Mermin, J.H. (2007). Estimating HIV incidence in voluntary counseling and testing clients in Uganda (1992–2003). Journal of Acquired Immune Deficiency Syndrome, 44, 99–105.CrossRefGoogle Scholar
  12. Blacker, J. (2004). The impact of AIDS on adult mortality: evidence from national and regional statistics. AIDS, 18 (Suppl 2), S19–26.PubMedCrossRefGoogle Scholar
  13. Bunnell, R., Ekwaru, J.P., Solberg, P., Wamai, N., Bikaako-Kajura, W., Were, W., Coutinho, A., Liechty, C., Madraa, E., Rutherford, G., & Mermin, J. (2006). Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural Uganda. AIDS, 20, 85–92.PubMedCrossRefGoogle Scholar
  14. Buve, A., Carael, M., Hayes, R.J., Auvert, B., Ferry, B., Robinson, N.J., Anagonou, S., Kanhonou, L., Laourou, M., Abega, S., Akam, E., Zekeng, L., Chege, J., Kahindo, M., Rutenberg, N., Kaona, F., Musonda, R., Sukwa, T., Morison, L., Weiss, H.A., & Laga, M. (2001a). Multicentre study on factors determining differences in rate of spread of HIV in sub-Saharan Africa: methods and prevalence of HIV infection. AIDS, 15 (Suppl 4), S5–14.CrossRefGoogle Scholar
  15. Buve, A., Carael, M., Hayes, R.J., Auvert, B., Ferry, B., Robinson, N.J., Anagonou, S., Kanhonou, L., Laourou, M., Abega, S., Akam, E., Zekeng, L., Chege, J., Kahindo, M., Rutenberg, N., Kaona, F., Musonda, R., Sukwa, T., Morison, L., Weiss, H.A., & Laga, M. (2001b). The multicentre study on factors determining the differential spread of HIV in four African cities: summary and conclusions. AIDS, 15 (Suppl 4), S127–31.CrossRefGoogle Scholar
  16. Cameron, D.W., Simonsen, J.N., D'Costa, L.J., Ronald, A.R., Maitha, G.M., Gakinya, M. Cheang, M.N., Ndinya-Achola, J.O., Piot, P., Brunham, R.C. & Plummer, F.A. (1989). Female to male transmission of human immunodeficiency virus type 1: risk factors for seroconversion in men. Lancet, 334, 403–7.CrossRefGoogle Scholar
  17. Carswell, J.W., Lloyd, G., & Howells, J. (1989). Prevalence of HIV-1 in east African lorry drivers. AIDS, 3, 759–61.PubMedCrossRefGoogle Scholar
  18. Central Bureau of Statistics, Kenya Ministry of Health, & ORC Macro (2004). Kenya Demographic & Health Survey 2003. Calverton, Maryland, USA.Google Scholar
  19. Cheluget, B., Baltazar, G., Orege, P., Ibrahim, M., Marum, L.H., & Stover, J. (2006). Evidence for population level declines in adult HIV prevalence in Kenya. Sexually Transmitted Infections, 82 (Suppl 1), i21–6.PubMedCrossRefGoogle Scholar
  20. Chen, H., Zha, J., Gowans, R.E., Camargo, P., Nishitani, J., McQuirter, J.L., Cole, S.W., Zack, J.A., & Liu, X. (2004). Alcohol enhances HIV type 1 infection in normal human oral keratinocytes by up-regulating cell-surface CXCR4 coreceptor. AIDS Research and Human Retroviruses, 20, 513–9.PubMedCrossRefGoogle Scholar
  21. Cleland, J., Ali, M.M., & Shah, I. (2006). Trends in protective behaviour among single vs. married young women in sub-Saharan Africa: the big picture. Reproductive Health Matters, 14, 17–22.PubMedCrossRefGoogle Scholar
  22. Cohen, S. (2004). Beyond slogans: lessons from Uganda's experience with ABC and HIV/AIDS. Reproductive Health Matters, 12, 132–5.PubMedGoogle Scholar
  23. Cook, R.L., & Clark, D.B. (2005). Is there an association between alcohol consumption and sexually transmitted diseases? A systematic review. Sexually Transmitted Diseases, 32, 156–64.PubMedCrossRefGoogle Scholar
  24. Council, N.A.C. (2005). Kenya HIV/AIDS Data Booklet.Google Scholar
  25. Coutinho, A. (2003). A situation analysis of HIV/AIDS in Uganda and the role of VCT. 1st Annual General Meeting of the AIDS Information Center, Uganda.Google Scholar
  26. Crafts, N., & Haacker, M. (2004). Chapter 6. Welfare implications of HIV/AIDS. Haacker The Macroeconomics of HIV/AIDS: International Monetary Fund.Google Scholar
  27. Das, P. (2005). Is abstinence-only threatening Uganda's HIV success story? Lancet Infectious Diseases, 5, 263–4.PubMedCrossRefGoogle Scholar
  28. del Mar Pujades Rodriguez, M., Obasi, A., Mosha, F., Todd, J., Brown, D., Changalucha, J., Mabey, D., Ross, D., Grosskurth, H., & Hayes, R. (2002). Herpes simplex virus type 2 infection increases HIV incidence: a prospective study in rural Tanzania. AIDS, 16, 451–62.CrossRefGoogle Scholar
  29. Epstein, H. (2007). The invisible cure: Africa, the West and the fight against AIDS. New York: Farrar, Straus and Giroux.Google Scholar
  30. Ferry, B., Carael, M., Buve, A., Auvert, B., Laourou, M., Kanhonou, L., de Loenzien, M., Akam, E., Chege, J., & Kaona, F. (2001). Comparison of key parameters of sexual behaviour in four African urban populations with different levels of HIV infection. AIDS, 15, (Suppl 4) S41–50.PubMedCrossRefGoogle Scholar
  31. Fleming, D.T., & Wasserheit, J.N. (1999). From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. Sexually Transmitted Infections, 75, 3–17.PubMedCrossRefGoogle Scholar
  32. Food and Agriculture Organisation (FAO). (2001). HIV/AIDS and Food Security Program, HIV/AIDS and Agriculture. FAO: Rome, June 2001. http://www.fao.org, accessed November 14, 2007.
  33. Food and Agriculture Organisation (FAO). (2002). The impact of HIV/AIDS on agricultural production and mainstreaming HIV/AIDS messages into agricultural extension in Uganda. Uganda Ministry of Agriculture, Animal Industry and Fisheries.Google Scholar
  34. Fothal, D., Mhalu, F.S., & Dahoma, A. (1986). AIDS in Tanzania. Second International Conference on AIDS. Paris, France.Google Scholar
  35. Freeman, E.E., Weiss, H.A., Glynn, J.R., Cross, P.L., Whitworth, J.A., & Hayes, R.J. (2006). Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS, 20, 73–83.PubMedCrossRefGoogle Scholar
  36. Garbus, L. (2004). HIV/AIDS in Tanzania. Country AIDS policy analysis project. San Francisco, AIDS Policy Research Center, UCSF.Google Scholar
  37. Garbus, L., & Marseille, E. (2003). HIV/AIDS in Uganda. Country AIDS policy analysis project. San Francisco, AIDS Policy Research Center, UCSF.Google Scholar
  38. Gilson, L., Mkanje, R., Grosskurth, H., Mosha, F., Picard, J., Gavyole, A., Todd, J., Mayaud, P., Swai, R., Fransen, L., Mabey, D., Mills, A., & Hayes, R. (1997). Cost-effectiveness of improved treatment services for sexually transmitted diseases in preventing HIV-1 infection in Mwanza Region, Tanzania. Lancet, 350, 1805–9.PubMedCrossRefGoogle Scholar
  39. Global HIV Prevention Working Group. (2003). Access to HIV prevention: closing the gap. Bill & Melinda Gates Foundation and Kaiser Family Foundation, Seattle.Google Scholar
  40. Glynn, J.R., Carael, M., Buve, A., Musonda, R.M., & Kahindo, M. (2003). HIV risk in relation to marriage in areas with high prevalence of HIV infection. Journal of Acquired Immune Deficiency Syndrome, 33, 526–35.Google Scholar
  41. Government of Kenya, & UNICEF Kenya Country Office. (2000). The Impact of HIV/AIDS on education in Kenya and the potential for using education in the widest sense for the prevention and control of HIV/AIDS.Google Scholar
  42. Gray, R.H., Kigozi, G., Serwadda, D., Makumbi, F., Watya, S., Nalugoda, F., Kiwanuka, N., Moulton, L.H., Chaudhary, M.A., Chen, M.Z., Sewankambo, N.K., Wabwire-Mangen, F., Bacon, M.C., Williams, C.F., Opendi, P., Reynolds, S.J., Laeyendecker, O., Quinn, T.C., & Wawer, M.J. (2007). Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised controlled trial. Lancet, 369, 657–66.PubMedCrossRefGoogle Scholar
  43. Gray, R.H., Kiwanuka, N., Quinn, T.C., Sewankambo, N.K., Serwadda, D., Mangen, F.W., Lutalo, T., Nalugoda, F., Kelly, R., Meehan, M., Chen, M.Z., Li, C., & Wawer, M.J. (2000). Male circumcision and HIV acquisition and transmission: cohort studies in Rakai, Uganda. Rakai Project Team. AIDS, 14, 2371–81.PubMedCrossRefGoogle Scholar
  44. Green, E.C., Halperin, D.T., Nantulya, V., & Hogle, J.A. (2006). Uganda's HIV prevention success: the role of sexual behavior change and the national response. AIDS and Behavior, 10, 335–46; 347–50.PubMedCrossRefGoogle Scholar
  45. Grosskurth, H., Mosha, F., Todd, J., Mwijarubi, E., Klokke, A., Senkoro, K., Mayaud, P., Changalucha, J., Nicoll, A., ka-Gina, G., Newell, J., Mugeye, K., Mabey, D., & Hayes, R. (1995). Impact of improved treatment of sexually transmitted diseases on HIV infection in rural Tanzania: randomised controlled trial. Lancet, 346, 530–6.PubMedCrossRefGoogle Scholar
  46. Guay, L.A., Musoke, P., Fleming, T., Bagenda, D., Allen, M., Nakabiito, C., Sherman, J., Bakaki, P., Ducar, C., Deseyve, M., Emel, L., Mirochnick, M., Fowler, M.G., Mofenson, L., Miotti, P., Dransfield, K., Bray, D., Mmiro, F., & Jackson, J.B. (1999). Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial Lancet, 354, 795–802.PubMedGoogle Scholar
  47. Hargreaves, J.R. (2002). Socioeconomic status and risk of HIV infection in an urban population in Kenya. Tropical Medicine and International Health, 7, 793–802.PubMedCrossRefGoogle Scholar
  48. Hyde, K.A.L., Ekatan, A., Kiage, P., & Barasa, C. (2001). HIV/AIDS and education in Uganda: window of opportunity. International Institute for Educational Planning.Google Scholar
  49. Jackson, J.B., Musoke, P., Fleming, T., Guay, L.A., Bagenda, D., Allen, M., Nakabiito, C., Sherman, J., Bakaki, P., Owor, M., Ducar, C., Deseyve, M., Mwatha, A., Emel, L., Duefield, C., Mirochnick, M., Fowler, M.G., Mofenson, L., Miotti, P., Gigliotti, M., Bray, D., & Mmiro, F. (2003). Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial. Lancet, 362, 859–68.PubMedCrossRefGoogle Scholar
  50. Joesoef, M.R., Cheluget, B., Marum, L.H., Wandera, C., Ryan, C.A., DeCock, K.M., & Chebet, K. (2003). Differential of HIV prevalence in women and men who attended sexually transmitted disease clinics at HIV sentinel surveillance sites in Kenya, 1990–2001. International Journal of STD and AIDS, 14, 193–6.PubMedCrossRefGoogle Scholar
  51. Johnson, B.A., & Khanna, S.K. (2004). Community health workers and home-based care programs for HIV clients. Journal of the National Medical Association, 96, 496–502.PubMedGoogle Scholar
  52. Jordan-Harder, B., Maboko, L., Mmbando, D., Riedner, G., Nagele, E., Harder, J., Kuchen, V., Kilian, A., Korte, R., & Sonnenburg, F.V. (2004). Thirteen years HIV-1 sentinel surveillance and indicators for behavioural change suggest impact of programme activities in south-west Tanzania. AIDS, 18, 287–94.PubMedCrossRefGoogle Scholar
  53. Kalichman, S.C., & Simbayi, L.C. (2004). Sexual assault history and risks for sexually transmitted infections among women in an African township in Cape Town, South Africa. AIDS Care, 16, 681–9.PubMedCrossRefGoogle Scholar
  54. Kamali, A., Nunn, A.J., Mulder, D.W., Van Dyck, E., Dobbins, J.G., & Whitworth, J.A. (1999). Seroprevalence and incidence of genital ulcer infections in a rural Ugandan population. Sexually Transmitted Infections, 75, 98–102.PubMedCrossRefGoogle Scholar
  55. Kamali, A., Quigley, M., Nakiyingi, J., Kinsman, J., Kengeya-Kayondo, J., Gopal, R., Ojwiya, A., Hughes, P., Carpenter, L.M., & Whitworth, J. (2003). Syndromic management of sexually-transmitted infections and behaviour change interventions on transmission of HIV-1 in rural Uganda: a community randomised trial. Lancet, 361, 645–52.PubMedCrossRefGoogle Scholar
  56. Kapiga, S.H., & Lugalla, J.L. (2002). Sexual behaviour patterns and condom use in Tanzania: results from the 1996 Demographic and Health Survey. AIDS Care, 14, 455–69.PubMedGoogle Scholar
  57. Kapiga, S.H., Lyamuya, E.F., Lwihula, G.K., & Hunter, D.J. (1998). The incidence of HIV infection among women using family planning methods in Dar es Salaam, Tanzania. AIDS, 12, 75–84.PubMedCrossRefGoogle Scholar
  58. Kapiga, S.H., Sam, N.E., Mlay, J., Aboud, S., Ballard, R.C., Shao, J.F., & Larsen, U. (2006). The epidemiology of HIV-1 infection in northern Tanzania: results from a community-based study. AIDS Care, 18, 379–87.PubMedCrossRefGoogle Scholar
  59. Kapiga, S.H., Sam, N.E., Bang, H., Ni, Q., Ao, T.T., Kiwelu, I., Chiduo, S., Ndibe, U., Seage, G., Coplan 3rd, P., Shao, J., Rosenberg, Z.F., & Essex, M. (2007). The role of Herpes simplex virus type 2 and other genital infections in the acquisition of HIV-1 among high-risk women in Northern Tanzania. Journal of Infectious Diseases, 195, 1260–9.PubMedCrossRefGoogle Scholar
  60. Karamagi, C.A., Tumwine, J.K., Tylleskar, T., & Heggenhougen, K. (2006). Intimate partner violence against women in eastern Uganda: implications for HIV prevention. BMC Public Health, 6, 284.PubMedCrossRefGoogle Scholar
  61. Kaul, R., Kimani, J., Nagelkerke, N.J., Fonck, K., Ngugi, E.N., Keli, F., MacDonald, K.S., Maclean, I.W., Bwayo, J.J., Temmerman, M., Ronald, A.R., & Moses, S. (2004). Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial. Journal of the American Medical Association, 291, 2555–62.PubMedCrossRefGoogle Scholar
  62. Kelly, R.J., Gray, R.H., Sewankambo, N.K., Serwadda, D., Wabwire-Mangen, F., Lutalo, T., & Wawer, M.J. (2003). Age differences in sexual partners and risk of HIV-1 infection in rural Uganda. Journal of Acquired Immune Deficiency Syndrome, 32, 446–51.CrossRefGoogle Scholar
  63. Kenya Ministry of Health. (2005). Kenya National HIV/AIDS Strategic Plan (KNASP) 2005–2010.Google Scholar
  64. Kilian, A.H., Gregson, S., Ndyanabangi, B., Walusaga, K., Kipp, W., Sahlmuller, G., Garnett, G.P., Asiimwe-Okiror, G., Kabagambe, G., Weis, P., & von Sonnenburg, F. (1999). Reductions in risk behaviour provide the most consistent explanation for declining HIV-1 prevalence in Uganda. AIDS, 13, 391–8.PubMedCrossRefGoogle Scholar
  65. Killewo, J., Nyamuryekunge, K., Sandstrom, A., Bredberg-Raden, U., Wall, S., Mhalu, F., & Biberfeld, G. (1990). Prevalence of HIV-1 infection in the Kagera region of Tanzania: a population-based study. AIDS, 4, 1081–5.PubMedCrossRefGoogle Scholar
  66. Killewo, J.Z., Sandstrom, A., Bredberg-Raden, U., Mhalu, F.S., Biberfeld, G., & Wall, S. (1993). Incidence of HIV-1 infection among adults in the Kagera region of Tanzania. International Journal of Epidemiology, 22, 528–36.PubMedCrossRefGoogle Scholar
  67. Kissling, E., Allison, E.H., Seeley, J.A., Russell, S., Bachmann, M., Musgrave, S.D., & Heck, S. (2005). Fisherfolk are among groups most at risk of HIV: cross-country analysis of prevalence and numbers infected. AIDS, 19, 1939–46.PubMedCrossRefGoogle Scholar
  68. Kwesigabo, G., Killewo, J., Urassa, W., Lugalla, J., Emmelin, M., Mutembei, A., Mhalu, F., Biberfeld, G., Wall, S., & Sandstrom, A. (2005). HIV-1 infection prevalence and incidence trends in areas of contrasting levels of infection in the Kagera region, Tanzania, 1987–2000. Journal of Acquired Immune Deficiency Syndrome, 40, 585–91.CrossRefGoogle Scholar
  69. Leigh, B.C., Temple, M.T., & Trocki, K.F. (1994). The relationship of alcohol use to sexual activity in a U.S. national sample. Social Science and Medicine, 39, 1527–35.PubMedCrossRefGoogle Scholar
  70. Loewenson, R., & Whiteside, A. (2001). HIV/AIDS: Implications for poverty reduction: Background paper prepared for the UNGASS on HIV/AIDS, 25–27th June 2001. United Nations Development Programme.Google Scholar
  71. Lugalla, J., Emmelin, M., Mutembei, A., Sima, M., Kwesigabo, G., Killewo, J., & Dahlgren, L. (2004). Social, cultural and sexual behavioral determinants of observed decline in HIV infection trends: lessons from the Kagera Region, Tanzania. Social Science and Medicine, 59, 185–98.PubMedCrossRefGoogle Scholar
  72. MacLaren, D. (1996). The Church Responds to HIV/AIDS. http://www.cafod.org.uk/hivaids/aidschurch.shtml. Caritas Internationalis, Rome.
  73. Martin, Jr., H.L., Nyange, P.M., Richardson, B.A., Lavreys, L., Mandaliya, K., Jackson, D.J., Ndinya-Achola, J.O., & Kreiss, J. (1998). Hormonal contraception, sexually transmitted diseases, and risk of heterosexual transmission of human immunodeficiency virus type 1. Journal of Infectious Diseases, 178, 1053–9.PubMedCrossRefGoogle Scholar
  74. Marum, E., Taegtmeyer, M., & Chebet, K. (2006). Scale-up of voluntary HIV counseling and testing in Kenya. Journal of the American Medical Association, 296, 859–862.PubMedCrossRefGoogle Scholar
  75. Matshalaga, N.R., & Powell, G. (2002). Mass orphanhood in the era of HIV/AIDS. British Medical Journal, 324, 185–6.PubMedCrossRefGoogle Scholar
  76. Mbulaiteye, S.M., Ruberantwari, A., Nakiyingi, J.S., Carpenter, L.M., Kamali, A., & Whitworth, J.A. (2000). Alcohol and HIV: a study among sexually active adults in rural southwest Uganda. International Journal of Epidemiology, 29, 911–5.PubMedCrossRefGoogle Scholar
  77. Mbulaiteye, S.M., Mahe, C., Whitworth, J.A., Ruberantwari, A., Nakiyingi, J.S., Ojwiya, A., & Kamali, A. (2002). Declining HIV-1 incidence and associated prevalence over 10 years in a rural population in south-west Uganda: a cohort study. Lancet, 360, 41–6.PubMedCrossRefGoogle Scholar
  78. Mhalu, F., Bredberg-Raden, U., Mbena, E., Pallangyo, K., Kiango, J., Mbise, R., Nyamuryekunge, K., & Biberfeld, G. (1987). Prevalence of HIV infection in healthy subjects and groups of patients in Tanzania. AIDS, 1, 217–21.PubMedGoogle Scholar
  79. Ministry of Health, Uganda. (2006). Uganda HIV/AIDS Sero-behavioural Survey 2004–2005. Calverton, Maryland, USA, Ministry of Health Uganda, and ORC Macro.Google Scholar
  80. Monasch, R., & Boerma, J.T. (2004). Orphanhood and childcare patterns in sub-Saharan Africa: an analysis of national surveys from 40 countries. AIDS, 18 (Suppl 2), S55–65.PubMedCrossRefGoogle Scholar
  81. Moore, A., Herrera, G., Nyamongo, J., Lackritz, E., Granade, T., Nahlen, B., Oloo, A., Opondo, G., Muga, R., & Janssen, R. (2001). Estimated risk of HIV transmission by blood transfusion in Kenya. Lancet, 358, 657–60.PubMedCrossRefGoogle Scholar
  82. Mshana, G.H., Wamoyi, J., Busza, J., Zaba, B., Changalucha, J., Kaluvya, S., & Urassa, M. (2006). Barriers to accessing antiretroviral therapy in Kisesa, Tanzania: a qualitative study of early rural referrals to the national program. AIDS Patient Care and STDs, 20, 649–57.PubMedCrossRefGoogle Scholar
  83. Msuya, S.E., Mbizvo, E., Hussain, A., Uriyo, J., Sam, N.E., & Stray-Pedersen, B. (2006). HIV among pregnant women in Moshi Tanzania: the role of sexual behavior, male partner characteristics and sexually transmitted infections. AIDS Research and Therapy, 3, 27.PubMedCrossRefGoogle Scholar
  84. Mwaluko, G., Urassa, M., Isingo, R., Zaba, B., & Boerma, J.T. (2003). Trends in HIV and sexual behaviour in a longitudinal study in a rural population in Tanzania, 1994–2000. AIDS, 17, 2645–51.PubMedCrossRefGoogle Scholar
  85. Nagot, N., Ouedraogo, A., Foulongne, V., Konate, I., Weiss, H.A., Vergne, L., Defer, M.C., Djagbare, D., Sanon, A., Andonaba, J.B., Becquart, P., Segondy, M., Vallo, R., Sawadogo, A., Van de Perre, P., & Mayaud, P. (2007). Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. New England Journal of Medicine, 356, 790–9.PubMedCrossRefGoogle Scholar
  86. National AIDS and STI Control Programme (NASCOP)- Ministry of Health (2005). AIDS in Kenya. 7th ed. Nairobi.Google Scholar
  87. Ngom, P., Binka, F.N., Phillips, J.F., Pence, B., & Macleod, B. (2001). Demographic surveillance and health equity in sub-Saharan Africa. Health Policy and Planning, 16, 337–44.PubMedCrossRefGoogle Scholar
  88. Nnko, S., Washija, R., Urassa, M., & Boerma, J.T. (2001). Dynamics of male circumcision practices in northwest Tanzania. Sexually Transmitted Diseases, 28, 214–8.PubMedGoogle Scholar
  89. O'Hare, B.A., Venables, J., Nalubeg, J.F., Nakakeeto, M., Kibirige, M., & Southall, D.P. (2005). Home-based care for orphaned children infected with HIV/AIDS in Uganda. AIDS Care, 17, 443–50.PubMedCrossRefGoogle Scholar
  90. Obasi, A., Mosha, F., Quigley, M., Sekirassa, Z., Gibbs, T., Munguti, K., Todd, J., Grosskurth, H., Mayaud, P., Changalucha, J., Brown, D., Mabey, D., & Hayes, R. (1999). Antibody to herpes simplex virus type 2 as a marker of sexual risk behavior in rural Tanzania. Journal of Infectious Diseases, 179, 16–24.PubMedCrossRefGoogle Scholar
  91. Obbo, C. (1993). HIV transmission through social and geographic networks in Uganda. Social Science and Medicine, 36, 949–55.PubMedCrossRefGoogle Scholar
  92. Okero, F.A., Aceng, E., Madraa, E., Namagala, E., & Serutoke, J. (2003). Scaling up antiretroviral therapy: experience in Uganda: case study. Geneva: World Health Organization.Google Scholar
  93. Over, M. (2004). Chapter 10. Impact of the HIV/AIDS epidemic on the health sectors in developing countries. Haacker The Macroeconomics of HIV/AIDS: International Monetary Fund.Google Scholar
  94. Parkhurst, J.O. (2002). The Ugandan success story? Evidence and claims of HIV-1 prevention. Lancet, 360, 78–80.PubMedCrossRefGoogle Scholar
  95. Piot, P., Plummer, F.A., Rey, M.A., Ngugi, E.N., Rouzioux, C., Ndinya-Achola, J.O., Veracauteren, G., D'Costa, L.J., Laga, M., Nsanze, H., Fransen, L., Haase, D., van der Groen, G., Brunham, R.C., Ronald, A.R., & Brun-Vezinet, F. (1987). Retrospective seroepidemiology of AIDS virus infection in Nairobi populations. Journal of Infectious Diseases, 155, 1108–12.PubMedGoogle Scholar
  96. Programme, S.A.C. (2003). STD/HIV/AIDS surveillance report, June 2003. Kampala, Uganda: Ministry of Health.Google Scholar
  97. Project, T.S. (2003). Tanzania: HIV/AIDS sector assessment and strategy recommendations. Washington, DC, US Agency for International Development, Dar es Salaam, Tanzania.Google Scholar
  98. Prospects, W.P. (2003). World population prospects: the 2002 revision. Highlights. World population prospects. Population Division of the Department of Economic and Social Affairs of United Nations Secretariat, New York.Google Scholar
  99. Riedner, G., Hoffmann, O., Rusizoka, M., Mmbando, D., Maboko, L., Grosskurth, H., Todd, J., Hayes, R., & Hoelscher, M. (2006). Decline in sexually transmitted infection prevalence and HIV incidence in female barworkers attending prevention and care services in Mbeya Region, Tanzania. AIDS, 20, 609–15.PubMedCrossRefGoogle Scholar
  100. Rugalema, G. (1999). HIV/AIDS and the commercial agricultural sector of Kenya: impact, vulnerability, susceptibility and coping strategies. Food and Agriculture Organization of the United Nations (FAO).Google Scholar
  101. Schoofs, M. (2007). Challenge for AIDS fighters: circumcising Africans safely. The Wall Street Journal. New York City.Google Scholar
  102. Serwadda, D., Mugerwa, R.D., Sewankambo, N.K., Lwegaba, A., Carswell, J.W., Kirya, G.B., Bayley, A.C., Downing, R.G., Tedder, R.S., Clayden, S.A., & Dalgleish, A.G. (1985). Slim disease: a new disease in Uganda and its association with HTLV-III infection. Lancet, 326, 849–52.CrossRefGoogle Scholar
  103. Serwadda, D., Gray, R.H., Sewankambo, N.K., Wabwire-Mangen, F., Chen, M.Z., Quinn, T.C., Lutalo, T., Kiwanuka, N., Kigozi, G., Nalugoda, F., Meehan, M.P., Ashley Morrow, R., & Wawer, M.J. (2003). Human immunodeficiency virus acquisition associated with genital ulcer disease and herpes simplex virus type 2 infection: a nested case-control study in Rakai, Uganda. Journal of Infect Diseases, 188, 1492–7.CrossRefGoogle Scholar
  104. Sewankambo, N.K., Gray, R.H., Ahmad, S., Serwadda, D., Wabwire-Mangen, F., Nalugoda, F., Kiwanuka, N., Lutalo, T., Kigozi, G., Li, C., Meehan, M.P., Brahmbatt, H., & Wawer, M.J. (2000). Mortality associated with HIV infection in rural Rakai District, Uganda. AIDS, 14, 2391–400.PubMedCrossRefGoogle Scholar
  105. Shafer, L.A., Biraro, S., Kamali, A., Grosskurth, H., Kirungi, W., Madraa, E., & Opio, A. (2006). HIV prevalence and incidence are no longer falling in Uganda – a case for renewed prevention efforts: Evidence from a rural population cohort 19892005, and from ANC surveillance. Abstract THLB0108. XVI International AIDS Conference, Toronto, Canada.Google Scholar
  106. Simbayi, L.C., Kalichman, S.C., Jooste, S., Mathiti, V., Cain, D., & Cherry, C. (2004). Alcohol use and sexual risks for HIV infection among men and women receiving sexually transmitted infection clinic services in Cape Town, South Africa. Journal of Studies on Alcohol, 65, 434–42.PubMedGoogle Scholar
  107. Stoneburner, R.L., & Low-Beer, D. (2004). Population-level HIV declines and behavioral risk avoidance in Uganda. Science, 304, 714–8.PubMedCrossRefGoogle Scholar
  108. Swai, R.O., Somi, G.G., Matee, M.I., Killewo, J., Lyamuya, E.F., Kwesigabo, G., Tulli, T., Kabalimu, T.K., Ng'ang'a, L., Isingo, R., & Ndayongeje, J. (2006). Surveillance of HIV and syphilis infections among antenatal clinic attendees in Tanzania-2003/2004. BMC Public Health, 6, 91.PubMedCrossRefGoogle Scholar
  109. TACAIDS (2002). National Multi-sectoral strategic framework on HIV/AIDS. Dar es Salaam.Google Scholar
  110. TACAIDS (2005). Tanzania HIV/AIDS Indicator Survey 2003–04. Calverton, Maryland, USA, TACAIDS, NBS, and ORC Macro.Google Scholar
  111. Temmerman, M., Ali, F.M., Ndinya-Achola, J., Moses, S., Plummer, F.A., & Piot, P. (1992). Rapid increase of both HIV-1 infection and syphilis among pregnant women in Nairobi, Kenya. AIDS, 6, 1181–5.PubMedCrossRefGoogle Scholar
  112. The Voluntary HIV-1 Counseling and Testing Efficacy Study Group. (2000). Efficacy of voluntary HIV-1 counselling and testing in individuals and couples in Kenya, Tanzania, and Trinidad: a randomised trial. Lancet, 356 (9224), 103–12.CrossRefGoogle Scholar
  113. Uganda AIDS Commission. (2005). National HIV/AIDS Atlas. Kampala. www.aidsuganda.org/texbits/ATLAS%20Format%20-%20081205.pdf
  114. Uganda AIDS Commission, & UNAIDS. (2000). The national strategic framework for HIV/AIDS activities in Uganda: 2000/01 to 2005/06. Kampala: Government of Uganda.Google Scholar
  115. UNAIDS (2006). Report on the global AIDS epidemic 2006. Geneva.Google Scholar
  116. Urassa, W., Kaaya, S., Mwakagile, D., O'Brien, M., Antelman, G., Hunter, D., Fawzi, W., & Msamanga, G. (2006). Evidence of a substantial decline in prevalence of HIV-1 infection among pregnant women: data from 1995 to 2003 in Dar es Salaam, Tanzania. Scandinavian Journal of Public Health, 34, 272–8.PubMedCrossRefGoogle Scholar
  117. Vallely, A., Kasindi, S., Hambleton, I.R., Knight, L., Chirwa, T., Balira, R., Changalucha, J., Watson-Jones, D., Everett, D., Gavyole, A., Moyes, J., Pujades-Rodriguez, M., Ross, D.A., & Hayes, R.J. (2007). Microbicides development program, Tanzania-baseline characteristics of an occupational cohort and reattendance at 3 months. Sexually Transmitted Diseases, 34, 638–43.PubMedCrossRefGoogle Scholar
  118. Wagner, H.U., Van Dyck, E., Roggen, E., Nunn, A.J., Kamali, A., Schmid, D.S., Dobbins, J.G., & Mulder, D.W. (1994). Seroprevalence and incidence of sexually transmitted diseases in a rural Ugandan population. International Journal of STD and AIDS, 5, 332–7.PubMedGoogle Scholar
  119. Walker, M. (2003). An assessment of home based care programs in Uganda: their strengths and weaknesses. Cambridge, Massachusetts, Harvard Center for Population and Development Studies.Google Scholar
  120. Watson-Jones, D., Changalucha, J., Weiss, H., Baisley, K., C. Cook, D. Everett, D.A. Ross, R.J. Hayes, & M. Rusizoka (2006). Baseline screening and risk factors for HIV and HSV-2 in an HSV-2 suppressive treatment trial in Tanzania. XVI International AIDS Conference, Toronto, Canada.Google Scholar
  121. Wawer, M.J., Eng, S.M., Serwadda, D., Sewankambo, N.K., Kiwanuka, N., Li, C., & Gray, R.H. (2001). Prevalence of Kaposi sarcoma-associated herpesvirus compared with selected sexually transmitted diseases in adolescents and young adults in rural Rakai District, Uganda. Sexually Transmitted Diseases, 28, 77–81.PubMedGoogle Scholar
  122. Wawer, M.J., Serwadda, D., Gray, R.H., Sewankambo, N.K., Li, C., Nalugoda, F., Lutalo, T., & Konde-Lule, J.K. (1997). Trends in HIV-1 prevalence may not reflect trends in incidence in mature epidemics: data from the Rakai population-based cohort, Uganda. AIDS, 11, 1023–30.PubMedCrossRefGoogle Scholar
  123. Wawer, M.J., Sewankambo, N.K., Serwadda, D., Quinn, T.C., Paxton, L.A., Kiwanuka, N., Wabwire-Mangen, F., Li, C., Lutalo, T., Nalugoda, F., Gaydos, C.A., Moulton, L.H., Meehan, M.O., Ahmed, S., & Gray, R.H. (1999). Control of sexually transmitted diseases for AIDS prevention in Uganda: a randomised community trial. Rakai Project Study Group. Lancet, 353, 525–35.PubMedCrossRefGoogle Scholar
  124. Weidle, P.J., Wamai, N., Solberg, P., Liechty, C., Sendagala, S., Were, W., Mermin, J., Buchacz, K., Behumbiize, P., Ransom, R.L., & Bunnell, R. (2006). Adherence to antiretroviral therapy in a home-based AIDS care programme in rural Uganda. Lancet, 368, 1587–94.PubMedCrossRefGoogle Scholar
  125. Weir, S.S., Pailman, C., Mahlalela, X., Coetzee, N., Meidany, F., & Boerma, J.T. (2003). From people to places: focusing AIDS prevention efforts where it matters most. AIDS, 17, 895–903.PubMedCrossRefGoogle Scholar
  126. Were, W., Mermin, J., Bunnell, R., Ekwaru, J.P., & Kaharuza, F. (2003). Home-based model for HIV voluntary counselling and testing. Lancet, 361, 1569.PubMedCrossRefGoogle Scholar
  127. White, R.G., Orroth, K.K., Korenromp, E.L., Bakker, R., Wambura, M., Sewankambo, N.K., Gray, R.H., Kamali, A., Whitworth, J.A., Grosskurth, H., Habbema, J.D., & Hayes, R.J. (2004). Can population differences explain the contrasting results of the Mwanza, Rakai, and Masaka HIV/sexually transmitted disease intervention trials?: A modeling study. Journal of Acquired Immune Deficiencey Syndrome, 37, 1500–13.CrossRefGoogle Scholar
  128. Whitworth, J.A., Mahe, C., Mbulaiteye, S.M., Nakiyingi J., Ruberantwari, A., Ojwiya, A., & Kamali, A. (2002). HIV-1 epidemic trends in rural south-west Uganda over a 10-year period. Tropical Medicine and International Health, 7, 1047–52.PubMedCrossRefGoogle Scholar
  129. WHO (2002). Coverage of selected health services for HIV/AIDS prevention and care in less developed countries in 2001. Geneva: World Health Organization.Google Scholar
  130. WHO. (2005a). "Summary country profile for HIV/AIDS treatment scale-up: Kenya." Retrieved September 10, 2007, from www.who.int/3by5/support/june2005_ken.pdf.
  131. WHO. (2005b). "Summary country profile for HIV/AIDS treatment scale-up: Tanzania." Retrieved September 10, 2007, from www.who.int/3by5/support/june2005_tza.pdf.
  132. WHO. (2005c). "Summary country profile for HIV/AIDS treatment scale-up: Uganda." Retrieved September 10, 2007, from www.who.int/3by5/support/june2005_uga.pdf.
  133. WHO. (2006). The World Health Report. Geneva, World Health Organisation.Google Scholar
  134. WHO/UNAIDS. (2007). New data on male circumcision and HIV prevention: Policy and programme implications: conclusions and recommendations. Geneva, UNAIDS.Google Scholar
  135. WHO/UNAIDS/UNICEF (2007). Towards universal access: scaling up priority HIV/AIDS interventions in the health sector: Progress report April 2007. Geneva: World Health Organization.Google Scholar
  136. Williamson, N.E., Liku, J., McLoughlin, K., Nyamongo, I.K., & Nakayima, F. (2006). A qualitative study of condom use among married couples in Kampala, Uganda. Reproductive Health Matters, 14, 89–98.PubMedCrossRefGoogle Scholar
  137. Wolff, B., Busza, J., Bufumbo, L., & Whitworth, J. (2006). Women who fall by the roadside: gender, sexual risk and alcohol in rural Uganda. Addiction, 101, 1277–84.PubMedCrossRefGoogle Scholar
  138. Zaba, B., Pisani, E., Slaymaker, E., & Boerma, J.T. (2004). Age at first sex: understanding recent trends in African demographic surveys. Sexually Transmitted Infections, 80 (Suppl 2), ii28–35.PubMedCrossRefGoogle Scholar
  139. Zablotska, I.B., Gray, R.H., Serwadda, D., Nalugoda, F., Kigozi, G., Sewankambo, N., Lutalo, T., Mangen, F.W., & Wawer, M. (2006). Alcohol use before sex and HIV acquisition: a longitudinal study in Rakai, Uganda. AIDS, 20, 1191–6.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Helen A. Weiss
    • 1
  • Corinne Merle
    • 1
  • David Serwadda
    • 2
  • Saidi H. Kapiga
    • 3
  1. 1.London School of Hygiene and Tropical MedicineLondonUK
  2. 2.Makerere University School of Public HealthKampalaUganda
  3. 3.Harvard School of Public HealthBostonUSA

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