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Renal Vasculitis in the Elderly

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The Aging Kidney in Health and Disease

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References

  1. Kohli, H.S., Bhat, A., Aravindan, et al. Spectrum of renal failure in elderly patients. Int. Urol. Nephrol. 2007; 23:23.

    Google Scholar 

  2. Hauer, H.A., Bajema, I.M., van Houwelingen, H.C., et al. Renal histology in ANCA-associated vasculitis: Differences between diagnostic and serologic subgroups. Kidney Int. 2002; 61:80–89.

    Article  PubMed  Google Scholar 

  3. Ulm, S., Hummel, M., Emig, M., et al. Leukocytoclastic vasculitis and acute renal failure after influenza vaccination in an elderly patient with myelodysplastic syndrome. Onkologie 2006; 29:470–472. Epub 2006 Sep 27.

    Google Scholar 

  4. Jennette, J.C., Falk, R.J., Andrassy, K., et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994; 37:187–192.

    Article  PubMed  CAS  Google Scholar 

  5. Muller, E., Schneider, W., Kettritz, U., Schmidt, W.A., Luft, F.C., Gobel, U. Temporal arteritis with pauci-immune glomerulonephritis: A systemic disease. Clin. Nephrol. 2004; 62:384–386.

    PubMed  CAS  Google Scholar 

  6. Jayne, D.R., Marshall, P.D., Jones, S.J., Lockwood, C.M. Autoantibodies to GBM and neutrophil cytoplasm in rapidly progressive glomerulonephritis. Kidney Int. 1990; 37:965–970.

    Article  PubMed  CAS  Google Scholar 

  7. Eisenberger, U., Fakhouri, F., Vanhille, P., et al. ANCA-negative pauci-immune renal vasculitis: Histology and outcome. Nephrol. Dial. Transplant 2005; 20: 1392–1399. Epub 2005 Apr 26.

    Article  PubMed  Google Scholar 

  8. Watts, R.A., Scott, D.G. Epidemiology of the vasculitides. Sem. Respir. Crit. Care Med. 2004; 25:455–464.

    Article  Google Scholar 

  9. Krafcik, S.S., Covin, R.B., Lynch, J.P., III, Sitrin, R.G. Wegener’s granulomatosis in the elderly. Chest 1996; 109:430–437.

    PubMed  CAS  Google Scholar 

  10. Vassallo, M., Shepherd, R.J., Iqbal, P., Feehally, I. Age-related variations in presentation and outcome in Wegener’s granulomatosis. J. Roy. Coll. Phys. Lond. 1997; 31:396–400.

    CAS  Google Scholar 

  11. Rychlik, I., Jancova, E., Tesar, V., et al. The Czech registry of renal biopsies. Occurrence of renal diseases in the years 1994–2000. Nephrol. Dial. Transplant 2004; 19:3040–3049. Epub 2004 Oct 26.

    Article  PubMed  Google Scholar 

  12. Hewins, P., Savage, C.O. ANCA and neutrophil biology. Kidney Blood Press. Res. 2003; 26:221–225.

    Article  PubMed  Google Scholar 

  13. Xiao, H., Heeringa, P., Hu, P., et al. Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J. Clin. Invest. 2002; 110:955–963.

    Article  PubMed  CAS  Google Scholar 

  14. Wang, Y., Zhao, M.H., Yu, J., et al. The clinical and pathological characteristics of Chinese elderly patients with anti-neutrophil cytoplasmic autoantibodies associated small vessel vasculitis. Exp. Gerontol. 2004; 39:1401–1405.

    Article  PubMed  CAS  Google Scholar 

  15. Abdulahad, W.H., van der Geld, Y.M., Stegeman, C.A., Kallenberg, C.G. Persistent expansion of CD4+ effector memory T cells in Wegener’s granulomatosis. Kidney Int. 2006; 70:938–947. Epub 2006 Jul 12.

    Article  PubMed  CAS  Google Scholar 

  16. Birck, R., Warnatz, K., Lorenz, H.M., et al. 15-Deoxyspergualin in patients with refractory ANCA-associated systemic vasculitis: A six-month open-label trial to evaluate safety and efficacy. J. Am. Soc. Nephrol. 2003; 14:440–447.

    Article  PubMed  CAS  Google Scholar 

  17. Frampton, G., Jayne, D.R., Perry, G.J., Lockwood, C.M., Cameron, J.S. Autoantibodies to endothelial cells and neutrophil cytoplasmic antigens in systemic vasculitis. Clin. Exp. Immunol. 1990; 82:227–232.

    Article  PubMed  CAS  Google Scholar 

  18. Booth, A.D., Almond, M.K., Burns, A., et al. Outcome of ANCA-associated renal vasculitis: A 5-year retrospective study. Am. J. Kidney Dis. 2003; 41:776–784.

    PubMed  Google Scholar 

  19. Harper, L., Savage, C.O. ANCA-associated renal vasculitis at the end of the twentieth century—A disease of older patients. Rheumatology (Oxford) 2005; 44:495–501. Epub 2004 Dec 21.

    Article  CAS  Google Scholar 

  20. Hauer, H.A., Bajema, I.M., Van Houwelingen, H.C., et al. Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico-histopathological analysis of 96 patients. Kidney Int. 2002; 62:1732–1742.

    Article  PubMed  Google Scholar 

  21. Merkel, P.A., Seo, P., Aries, P., et al. Current status of outcome measures in vasculitis: Focus on Wegener’s granulomatosis and microscopic polyangiitis. Report from OMERACT 7. J. Rheumatol. 2005; 32:2488–2495.

    PubMed  Google Scholar 

  22. De Groot, K., Rasmussen, N., Bacon, P.A., et al. Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum. 2005; 52:2461–2469.

    Article  PubMed  CAS  Google Scholar 

  23. Jayne, D., Rasmussen, N., Andrassy, K., et al. A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. N. Engl. J. Med. 2003; 349:36–44.

    Article  PubMed  CAS  Google Scholar 

  24. Le Thi Huong, D., Wechsler, B., Piette, J.C., et al. [Wegener’s granulomatosis in elderly subjects. 37 cases.] [in French] Presse Med. 1988; 17:2379–2382.

    PubMed  CAS  Google Scholar 

  25. Nada, A.K., Torres, V.E., Ryu, J.H., Lie, J.T., Holley, K.E. Pulmonary fibrosis as an unusual clinical manifestation of a pulmonary-renal vasculitis in elderly patients. Mayo Clin. Proc. 1990; 65:847–856.

    PubMed  CAS  Google Scholar 

  26. Jayne, D.R., Rasmussen, N. Treatment of antineutrophil cytoplasm autoantibody-associated systemic vasculitis: Initiatives of the European Community Systemic Vasculitis Clinical Trials Study Group. Mayo Clin. Proc. 1997; 72:737–747.

    Article  PubMed  CAS  Google Scholar 

  27. de Groot, K., Adu, D., Savage, C.O. The value of pulse cyclophosphamide in ANCA-associated vasculitis: Meta-analysis and critical review. Nephrol. Dial. Transplant 2001; 16:2018–2027.

    Article  PubMed  Google Scholar 

  28. Hoffman, G.S., Kerr, G.S., Leavitt, R.Y., et al. Wegener granulomatosis: An analysis of 158 patients. Ann. Intern. Med. 1992; 116:488–498.

    PubMed  CAS  Google Scholar 

  29. Haubitz, M., Bohnenstengel, F., Brunkhorst, R., Schwab, M., Hofmann, U., Busse, D. Cyclophosphamide pharmacokinetics and dose requirements in patients with renal insufficiency. Kidney Int. 2002; 61:1495–1501.

    Article  PubMed  CAS  Google Scholar 

  30. Pusey, C.D., Rees, A.J., Evans, D.J., Peters, D.K., Lockwood, C.M. Plasma exchange in focal necrotizing glomerulonephritis without anti-GBM antibodies. Kidney Int. 1991; 40:757–763.

    Article  PubMed  CAS  Google Scholar 

  31. Boomsma, M.M., Stegeman, C.A., van der Leij, M.J., et al. Prediction of relapses in Wegener’s granulomatosis by measurement of antineutrophil cytoplasmic antibody levels: A prospective study. Arthritis Rheum. 2000; 43:2025–2033.

    Article  PubMed  CAS  Google Scholar 

  32. Sanders, J.S., Huitma, M.G., Kallenberg, C.G., Stegeman, C.A. Prediction of relapses in PR3-ANCA-associated vasculitis by assessing responses of ANCA titres to treatment. Rheumatology (Oxford) 2006; 45:724–729. Epub 2006 Jan 6.

    Article  CAS  Google Scholar 

  33. Jayne, D.R., Chapel, H., Adu, D., et al. Intravenous immunoglobulin for ANCA-associated systemic vasculitis with persistent disease activity. Quar. J. Med. 2000; 93:433–439.

    CAS  Google Scholar 

  34. Ito-Ihara, T., Ono, T., Nogaki, F., et al. Clinical efficacy of intravenous immunoglobulin for patients with MPO-ANCA-associated rapidly progressive glomerulonephritis. Nephron Clin. Pract. 2006; 102:c35–42. Epub 2005 Sep 19.

    Article  PubMed  CAS  Google Scholar 

  35. Etanercept plus standard therapy for Wegener’s granulomatosis. N. Engl. J. Med. 2005; 352:351–361.

    Google Scholar 

  36. Booth, A., Harper, L., Hammad, T., et al. Prospective study of TNF alpha blockade with infliximab in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis. J. Am. Soc. Nephrol. 2004; 15:717–721.

    Article  PubMed  CAS  Google Scholar 

  37. Smith, K.G., Jones, R.B., Burns, S.M., Jayne, D.R. Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment. Arthritis Rheum. 2006; 54:2970–2982.

    Article  PubMed  CAS  Google Scholar 

  38. de Lind van Wijngaarden, R.A., Hauer, H.A., Wolterbeek, R., et al. Clinical and histologic determinants of renal outcome in ANCA-associated vasculitis: A prospective analysis of 100 patients with severe renal involvement. J. Am. Soc. Nephrol. 2006; 17:2264–2274. Epub 2006 Jul 6.

    Google Scholar 

  39. Rutgers, A., Slot, M., van Paassen, P., van Breda Vriesman, P., Heeringa, P., Tervaert, J.W. Coexistence of anti-glomerular basement membrane antibodies and myeloperoxidase-ANCAs in crescentic glomerulonephritis. Am. J. Kidney Dis. 2005; 46:253–262.

    Article  PubMed  Google Scholar 

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Authors
  1. David Jayne
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Editor information

Editors and Affiliations

  1. Departamento de Medicina, University of Salamanca, Salamanca, Spain

    Juan F. MachasNúñez M.D., Ph.D (Profesor Titular de Medicina) (Profesor Titular de Medicina)

  2. Guy’s King’s and St. Thomas’ School of Medicine King’s College, London, UK

    J. Stewart Cameron M.D., B.Sc., FRCP (Emeritus Professor of Renal Medicine) (Emeritus Professor of Renal Medicine)

  3. Toronto Western Hospital, Toronto, Ontario, Canada

    Dimitrios G. Oreopoulos M.D., Ph.D. (Professor of Medicine) (Professor of Medicine)

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Jayne, D. (2008). Renal Vasculitis in the Elderly. In: MachasNúñez, J.F., Cameron, J.S., Oreopoulos, D.G. (eds) The Aging Kidney in Health and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72659-5_20

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  • DOI: https://doi.org/10.1007/978-0-387-72659-5_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-72658-8

  • Online ISBN: 978-0-387-72659-5

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