Hypertension in the Elderly

  • José A. Garcia-Donaire
  • José Luís Rodicio Díaz
  • Luis M. Ruilope


Arterial Stiffness Systolic Hypertension Target Organ Damage Isolate Systolic Hypertension Hypertension Guideline 
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  1. National High Blood Pressure Education Program Coordinating Committee. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Hypertension 2003; 42:1206–1252.Google Scholar
  2. Ezzati, M., Lopez, A.D., Rogers, A., van der Hoorn, S., Murray, C.J. Comparative Risk Assessment Collaborating Group. Selected major risk factors and global and regional burden of disease. Lancet 2003; 360:1347–1360.CrossRefGoogle Scholar
  3. Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Prospect. Studies Collabor. Lancet 2002; 360:1903–1913.Google Scholar
  4. Banegas, J.R., Segura, J., Ruilope, L.M., Luque, M., García-Robles, R., et al. Blood pressure control and physician management of hypertension in hospital hypertension units in Spain. Hypertension 2004; 43:1338–1344.PubMedCrossRefGoogle Scholar
  5. ESH/ESC Hypertension Guidelines Committee. Practice guidelines for primary care physicians: 2003 ESH/ESC hypertension guidelines. J. Hypertens. 2003; 21:1779–1786.CrossRefGoogle Scholar
  6. Plante, G.E. Impact of aging on the body’s vascular system. Metabolism 2003; 52:31–35.PubMedCrossRefGoogle Scholar
  7. Messerly, F.H., Ventura, H.O., Glade, L.B., Sundgaard, K., Dunn, F.G., Frohlich, E.D. Essential hypertension in the elderly: Hemodynamics, intravascular volume, plasma renin activity and circulating catecholamine levels. Lancet 1983; 2:983–986.CrossRefGoogle Scholar
  8. Amery, A., Wasir, H., Bulpitt, C. et al. Aging and the cardiovascular system. Acta Cardiol. 1978; 33:443–448.PubMedGoogle Scholar
  9. Macías-Núñez, J.F., Garcia Iglesias, C., Baudia, A., Rodriguez Gomes, J.L., Corbacho, J.L., Tabernero, J.M., De Castro, S. Renal handling of sodium in old people. Age and Ageing 1978; 7:178–189.PubMedCrossRefGoogle Scholar
  10. Nichols, W.W., O’Rourke, M.F. McDonald’s Blood Flow in Arteries: Theoretical, Experimental and Principles, 3rd ed. London: Edward Arnold. 1990.Google Scholar
  11. Nichols, W.W., Edwards, D.G. Arterial elastance and wave reflection augmentation of systolic blood pressure: Deleterious effects and implications for therapy. J. Cardiovasc. Pharmacol. Ther. 2001; 6:5–21.PubMedCrossRefGoogle Scholar
  12. Staessen, J., Gasowsky, J., Wang Ji, G., Thijs, L., Den Hond, E., Boissel, J.P., et al. Risks of untreated and treated isolated systolic hypertension in the elderly: Meta-analysis of outcome trials. Lancet 2000; 355:865–872.PubMedCrossRefGoogle Scholar
  13. Gueyffer, F., Bulpitt, C., Boissel, J.P., Schron, E., Ekbom, T., Fagard, R., et al. Antyhypertensive drugs in very old people: A subgroup meta-analysis of randomised controlled trials. Lancet 1999; 353:793–796.CrossRefGoogle Scholar
  14. Kaplan, N. Clinical Hypertension, 8th ed. Philadelphia: Williams and Wilkins Lippincott. 2002.Google Scholar
  15. Whelton, P.K., Appel, L.J., Espeland, M.A., et al. Sodium reduction and weight loss in the treatment of hypertension in older persons. JAMA 1998; 279:839–846.PubMedCrossRefGoogle Scholar
  16. Elliot, W.J. Management of hypertension in the very elderly patient. Hypertension 2004; 44:800–804.CrossRefGoogle Scholar
  17. Dahlof, B., Sever, P.S., Poulter, N.R., et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial. Lancet 2005; 366:895–906.PubMedCrossRefGoogle Scholar
  18. Chalmers, J., Castaigne, A., Morgan, T., Chastang, C. Long-term efficacy of a new, fixed, very-low-dose angiotensin-converting enzyme-inhibitor/diuretic combination as first-line therapy in elderly hypertensive patients. J. Hypertens. 2000; 18:327–337.PubMedCrossRefGoogle Scholar
  19. SHEP Co-operative Research Group: Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results on the systolic hypertension in the elderly program (SHEP). JAMA 1991; 265:3255–3264.Google Scholar
  20. Staessen, J., Fagrad, R., Thijs, L., et al. Morbidity and mortality in the placebo controlled European Trial on Isolated Systolic Hypertension in the Elderly (SYST-EUR). Lancet 1997; 360:757–764.CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • José A. Garcia-Donaire
  • José Luís Rodicio Díaz
  • Luis M. Ruilope

There are no affiliations available

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