General Anesthesia in a Patient with Chronic Amphetamine Use
You are assigned to anesthetize a 59-yr-old female for a total hip replacement. Her history is significant for depression and she has taken dextroamphetamine 15 mg b.d. for over 3yr. Would you proceed or would you recommend discontinuing amphetamine therapy before general anesthesia, and thereby delay the surgery?
KeywordsGeneral Anesthesia Elective Surgical Patient Chronic Amphetamine Respiratory Stimulant Peripheral Nerve Terminal
- 1.Healzer JM, Fisher SP, Brook MW, Brock-Utne JG. General anesthesia is a patient on long-term amphetamine therapy: Is there cause for concern? Anesth Analg 2000;91:758-759.Google Scholar
- 4.Hardman JG, Limbird LE. Amphetamine: The pharmacological basis of thera-peutics. 1996;219-221.Google Scholar