General Approach to Molecular Pathology
Part of the Molecular Pathology Library book series (MPLB, volume 1)
Once a highly specialized subdiscipline of laboratory medicine, molecular diagnostics now infiltrates all of anatomic and clinical pathology. The shift from dependence on a few, relatively cumbersome methods to a wider range of technologies has facilitated this expansion. In addition, the completion of the Human Genome Project and the growing amount of sequence data related to infection, cancer, and other disease states have yielded additional applications of molecular biology for the clinical laboratory (Figure 7.1). As the various phases of testing can be automated in many instances, molecular biologic experience is no longer a prerequisite. In fact, performance of nucleic acid extraction and amplification in a tabletop unit is possible.1, 2 Increasingly, miniaturization will further move molecular testing to the point of care.3
KeywordsMolecular Pathology Nucleic Acid Extraction Molecular Beacon Sequence Read Length Molecular Biologic Experience
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© Springer Science+Business Media, LLC. 2008