Histiocytic Diseases of the Lung

  • Carol Farver
  • Tracey L. Bonfield
Part of the Molecular Pathology Library book series (MPLB, volume 1)


Histiocytic lesions of the lung are a group of diseases that arise out of defects in the lung’s macrophage population. Although histiocytes play a major role in many diseases of the lung, including granulomatous diseases (mycobacterial and fungal infections, sarcoidosis)1 and other interstitial lung disease,2 we discuss only those lesions with the primary defect in the lung histiocyte or those systemic diseases with notable lung involvement. These include pulmonary Langerhans cell histiocytosis, Erdheim-Chester disease, Niemann-Pick disease, Gaucher’s disease, and Hermansky-Pudlak syndrome.


Interstitial Lung Disease Lamellar Body Gauche Cell Pulmonary Alveolar Proteinosis Pudlak Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • Carol Farver
    • 1
  • Tracey L. Bonfield
    • 2
  1. 1.Pulmonary Pathology, Department of Anatomic PathologyCleveland Clinic FoundationClevelandUSA
  2. 2.Department of Pediatric PulmonaryCase Western Reserve University School of MedicineCleveland

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