Molecular Pathology of Pediatric Tumors of the Lung

  • Josefine M. Heim-Hall
Part of the Molecular Pathology Library book series (MPLB, volume 1)


Primary lung tumors, both benign and malignant, are overall rare in the pediatric population. Among 166 cases seen at the Armed Forces Institute between 1950 and 1989, malignant tumors were more frequent than benign tumors, with a ratio of 1 : 1.68. Inflammatory myofibroblastic tumor, also known as inflammatory pseudotumor or plasma cell granuloma, is the most common benign pediatric lung tumor and is discussed later. Epithelial lung malignancies are rare in childhood. Although histologic subtypes are similar to those that occur in adults, the frequencies of types differ, with carcinoid tumors being the most common.1 There is no known association of environmental or genetic factors and the development of epithelial malignancies in children. Pleuropulmonary blastoma, discussed later, is truly a tumor of childhood and never occurs in adults. Thoracopulmonary small round cell tumor, also called Askin’s tumor, is not restricted to childhood but is most common in adolescents and young adults and will therefore be discussed here as well.


Anaplastic Lymphoma Kinase Malignant Peripheral Nerve Sheath Tumor Anaplastic Large Cell Lymphoma Congenital Cystic Adenomatoid Malformation Small Round Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • Josefine M. Heim-Hall
    • 1
  1. 1.Department of PathologyUniversity of Texas Health Science Center at San AntonioSan AntonioUSA

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